DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6a16 and BAS1

DIOPT Version :9

Sequence 1:	NP_001285631.1	Gene:	Cyp6a16 / 19836250	FlyBaseID:	FBgn0031726	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_180239.1	Gene:	BAS1 / 817212	AraportID:	AT2G26710	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	552	Identity:	134/552 - (24%)
Similarity:	229/552 - (41%)	Gaps:	126/552 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LLLLTSLLSFL----LGYLRYR-------FTYWELRGIPQLRPHFLFGHFFRL------QSVH-- 50
            :|:|:.:||.:    :..|.:|       |:...:||.|.   ||..|:...|      .|.|
plant    13 VLVLSVILSLVIVKGMSLLWWRPRKIEEHFSKQGIRGPPY---HFFIGNVKELVGMMLKASSHPM 74

  Fly    51 -YS-ELLQETYDAFRGSAKVAGT--YVFLRP--MAVVLDLDLVKAVLIRDFNNFVDRRSFHGDPL 109
             :| .:|......:....|:.|.  .|:..|  ...|.|.||::.:..:  :.|.::...|  ||
plant    75 PFSHNILPRVLSFYHHWRKIYGATFLVWFGPTFRLTVADPDLIREIFSK--SEFYEKNEAH--PL 135

  Fly   110 TA-----NLFNLQGEEWRNLRTKLSPTFTSGKMKYMFGTVSTVAQQLGGTFDELVGSQGAV-LEL 168
            ..     .|.:|:||:|.:.|..:||||....:|.:...|......:...:.:.:...|.| :::
plant   136 VKQLEGDGLLSLKGEKWAHHRKIISPTFHMENLKLLVPVVLKSVTDMVDKWSDKLSENGEVEVDV 200

  Fly   169 HDLMARYTTDVIGSCAFGTECSSLREPQAEFR----QV-------------GRRIFRNSNRSIRW 216
            ::.....|.|||...|||   ||..:.:|.||    |:             |.|.|........|
plant   201 YEWFQILTEDVISRTAFG---SSYEDGRAVFRLQAQQMLLCAEAFQKVFIPGYRFFPTRGNLKSW 262

  Fly   217 RIFKMTYLSSLAKLGLPVRILHPDITKFFNRIVRETVELRERENI-----------RRNDFMDLL 270
            ::.|                   :|.|...:::.     |.|:|.           ...|.:.|:
plant   263 KLDK-------------------EIRKSLLKLIE-----RRRQNAIDGEGEECKEPAAKDLLGLM 303

  Fly   271 LDLRRQENGKGLTMEQMAAQAFVFFVAGFETSSSNMSYALFELAKNQDVQQKLRMEINDSIGKHG 335
            :      ..|.:|::.:..:...||.||.:|:|:.:::....|:.:.:.|.|.|.|:....|...
plant   304 I------QAKNVTVQDIVEECKSFFFAGKQTTSNLLTWTTILLSMHPEWQAKARDEVLRVCGSRD 362

  Fly   336 KLTYEAMMEMPYLDQTITETLRKYPALSSLTRLASED-----YEIPSPDGGDPVVLEKGTSVHIP 395
            ..|.:.::::..|...:.|:||.||.:.:..|.|..|     |:||.           ||.:.||
plant   363 VPTKDHVVKLKTLSMILNESLRLYPPIVATIRRAKSDVKLGGYKIPC-----------GTELLIP 416

  Fly   396 VLAIHYDPEVY-PEPHEFRPERFAPDACR-ERHPTAFLGFGDGPRNCIGLRFGRMQVKVGLITLL 458
            ::|:|:|..:: .:.:||.|.|||....| .:||..|:.||.|.|.|||.....:|.|:.|..::
plant   417 IIAVHHDQAIWGNDVNEFNPARFADGVPRAAKHPVGFIPFGLGVRTCIGQNLAILQAKLTLAVMI 481

  Fly   459 RRFRFSLPP---GSPTQLKVTKRNLILLPSDG 487
            :||.|.|.|   .:||.|      ::|.|..|
plant   482 QRFTFHLAPTYQHAPTVL------MLLYPQHG 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a16	NP_001285631.1	p450	32..492	CDD:278495	125/514 (24%)
BAS1	NP_180239.1	CYP734	85..509	CDD:410732	116/477 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810