Protein Alignment Cyp6a16 and Cyp3a25

DIOPT Version :9

• Sequence 1: NP_001285631.1
• Gene: Cyp6a16 / 19836250
• FlyBaseID: FBgn0031726
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 510
• Identity: 168/510 - (32%)
• Similarity: 278/510 - (54%)
• Gaps: 51/510 - (10%)

  Fly     5 LLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFLFGHFFRLQSVHYSELLQETYDAFRGSAKVA 69
            :||:|||:.|.: |..|....::..|||..:|..|.|..|.    :|..:.:...|.::...|:.
Mouse    13 VLLVTSLVLFYI-YGTYSHGLFKKLGIPGPKPLPLLGTIFN----YYDGMWKFDEDCYKKYGKIW 72

  Fly    70 GTYVFLRPMAVVLDLDLVKAVLIRD-FNNFVDRRSFHGDPLTANLFNL-QGEEWRNLRTKLSPTF 132
            |.|...:|:..::|.:::|.||::: ::.|.:||.|...........: :.|||:.|||.|||||
Mouse    73 GFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRFFGPVGFMKKAITISEDEEWKRLRTLLSPTF 137

  Fly   133 TSGKMKYMFGTVSTVAQQLGGTFDELVGS------QGAVLELHDLMARYTTDVIGSCAFGTECSS 191
            ||||:|.||    .:.:|.|   |.||.:      :|..:.:.|:...|:.|||...:||....|
Mouse   138 TSGKLKEMF----PIMRQYG---DILVRNLRREEEKGEPISMKDIFGAYSMDVITGTSFGVNVDS 195

  Fly   192 LREPQAEFRQVGRRIFRNSNRSIRWRIFK--------MTYLSSLAKLGLPVRILHPDITKFFNRI 248
            |..||..|.|..::|       ::::||.        ..:|:.:.:: |...|...|...||.:.
Mouse   196 LNNPQDPFVQKAKKI-------LKFKIFDPFLLSIILFPFLTPIYEM-LNFSIFPRDSMNFFKKF 252

  Fly   249 VRETVELRERENIR-RNDFMDLLLDLRR---QENGKGLTMEQMAAQAFVFFVAGFETSSSNMSYA 309
            |:...:.|...|.: |.||:.|:::.:.   ||:.|.|:..:|||||.:|...|::.:|:::|..
Mouse   253 VKRMKKERLASNQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAVIFIFGGYDATSTSISLI 317

  Fly   310 LFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTITETLRKYPALSSLTRLASEDYE 374
            ::|||.:.|||:||:.||:.::.....:||:|:|:|.|||..:.|:||.||....|.|::.:|.|
Mouse   318 MYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVVNESLRLYPIAIRLERVSKKDVE 382

  Fly   375 IPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPEPHEFRPERFAPDACRERHPTAFLGFGDGPRN 439
            |      :.|.:.|||.|.||:..:|.:||.:|||.||.||||:.:......|..::.||:||||
Mouse   383 I------NGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERFSKENKGNIDPYIYMPFGNGPRN 441

  Fly   440 CIGLRFGRMQVKVGLITLLRRFRFSLPPGSPTQ--LKVTKRNLILLPSDGVRLQV 492
            |||:||..:.:|:.:|.:|:  .|::.|...||  ||:: |..|..|...:.|:|
Mouse   442 CIGMRFALISIKLAVIGVLQ--NFTVQPCEETQIPLKIS-REPIFQPEKPIILKV 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a16	NP_001285631.1	p450	32..492	CDD:278495	157/481 (33%)
Cyp3a25	NP_062766.2	p450	39..493	CDD:278495	157/481 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820