Protein Alignment Cyp6a16 and Cyp3a2

DIOPT Version :9

• Sequence 1: NP_001285631.1
• Gene: Cyp6a16 / 19836250
• FlyBaseID: FBgn0031726
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: NP_695224.3
• Gene: Cyp3a2 / 266682
• RGDID: 708379
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 521
• Identity: 160/521 - (30%)
• Similarity: 264/521 - (50%)
• Gaps: 65/521 - (12%)

  Fly     4 TLLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFLFGHFFRLQSVHYSELLQETYDAFRGSAKV 68
            |.:||..:|..|.....:|...::.:|||..:|....|....    :|..|.:...:.::...|:
  Rat    11 TWVLLAVILVLLYRLGTHRHGIFKKQGIPGPKPLPFLGTVLN----YYKGLGRFDMECYKKYGKI 71

  Fly    69 AGTYVFLRPMAVVLDLDLVKAVLIRD-FNNFVDRRSFHGDPLTANLFNL-QGEEWRNLRTKLSPT 131
            .|.:....|:..::|.:::|.||::: |:.|.:||.|....:.....:: :.|||:..|..||||
  Rat    72 WGLFDGQTPVFAIMDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAVSVAKDEEWKRYRALLSPT 136

  Fly   132 FTSGKMKYMFGTVSTVAQQLGGTFDELV------GSQGAVLELHDLMARYTTDVIGSCAFGTECS 190
            ||||::|.||    .:.:|.|   |.||      ...|..:.:..:...|:.|||.|.:||....
  Rat   137 FTSGRLKEMF----PIIEQYG---DILVKYLKQEAETGKPVTMKKVFGAYSMDVITSTSFGVNVD 194

  Fly   191 SLREPQAEFRQVGRRIFRNSNRSIRWRIFKMTYLSSLAKLGLPVRILHPDIT------------- 242
            ||..|:..|.:..:::       :|:..|...:||.         :|.|.:|
  Rat   195 SLNNPKDPFVEKTKKL-------LRFDFFDPLFLSV---------VLFPFLTPIYEMLNICMFPK 243

  Fly   243 ---KFFNRIVRETVELR-ERENIRRNDFMDLLLDL----RRQENGKGLTMEQMAAQAFVFFVAGF 299
               .||.:.|....|.| :.::..|.||:.|:|:.    :.:.:.|.|:..::.||:.:|..||:
  Rat   244 DSIAFFQKFVHRIKETRLDSKHKHRVDFLQLMLNAHNNSKDEVSHKALSDVEIIAQSVIFIFAGY 308

  Fly   300 ETSSSNMSYALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTITETLRKYPALSS 364
            ||:||.:|:.|:.||.:.|:|:||:.||:.::......||:.:|||.|||..:.||||.||..:.
  Rat   309 ETTSSTLSFVLYFLATHPDIQKKLQEEIDGALPSKAPPTYDIVMEMEYLDMVLNETLRLYPIGNR 373

  Fly   365 LTRLASEDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPEPHEFRPERFAPDACRERHPTA 429
            |.|:..:|.|:      |.:.:.||:.|.||..|:|:||:.:|:|.||.||||:.:......|..
  Rat   374 LERVCKKDIEL------DGLFIPKGSVVTIPTYALHHDPQHWPKPEEFHPERFSKENKGSIDPYV 432

  Fly   430 FLGFGDGPRNCIGLRFGRMQVKVGLITLLRRFRFSLPPGSPTQLKV-TKRNLILLPSDGVRLQVD 493
            :|.||:|||||||:||..|.:|:.|..:|:.|.|.  |...||:.: ..|..||.|...:.|:|.
  Rat   433 YLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQ--PCKETQIPLKLSRQAILEPEKPIVLKVL 495

  Fly   494 P 494
            |
  Rat   496 P 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a16	NP_001285631.1	p450	32..492	CDD:278495	150/489 (31%)
Cyp3a2	NP_695224.3	CYP3A	67..493	CDD:410743	144/456 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8924
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.870