Protein Alignment Cyp6a16 and cyp-13A2

DIOPT Version :10

• Sequence 1: NP_001285631.1
• Gene: Cyp6a16 / 19836250
• FlyBaseID: FBgn0031726
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 518
• Identity: 147/518 - (28%)
• Similarity: 240/518 - (46%)
• Gaps: 74/518 - (14%)

  Fly     1 MDFTLLLLTSLLSFLLGYLRYRFTYWELRGI--PQLRPHFLFGHFFRLQSV---HYSELLQETYD 60
            :.|.|.:..|:...:|.|..:.:|||..:|:  |:.||      |..:..|   |.:..|.:..:
 Worm     3 LGFVLAVTFSIFLGILTYYLWIWTYWMRKGVKGPRGRP------FVGVLDVLLEHETPGLIKLGE 61

  Fly    61 AFRGSAKVAGTYVFLRPMAVVLDLDLVKAVLIRDFNNFVDRR--SFHGDP---LTANLFNLQGEE 120
            ..:...||.|.....:...||.|..:|..:.::.|:||..|:  ...|:|   ...:|...||..
 Worm    62 WTKKYGKVYGYTDGTQRTLVVADPAMVHEIFVKQFDNFYGRKLNPIQGNPEKEQRVHLLAAQGYR 126

  Fly   121 WRNLRTKLSPTFTSGKMKYMFGTVSTVAQQLGGTFDELVGSQGAVLELHDLMARYTTDVIGSCAF 185
            |:.|||..|.:|::..:|.|..||...|.:|....::.... |..:::......||.||||..|.
 Worm   127 WKRLRTISSQSFSNASLKKMKRTVEDSALELLRHIEKQTAG-GEQIDMLRFYQEYTMDVIGRFAM 190

  Fly   186 G-TECSSLREPQAEFRQVGRRIFRNSNRSIRWRIFKMTYLSSLAKLGLPVRILHPDITKFFNRI- 248
            | |:....:.|   ...|.|.||..|.:::      |........:|..:|    |:|..|.||
 Worm   191 GQTDSMMFKNP---IVNVVREIFCGSRKNL------MLICQVFPPIGQFIR----DLTFKFPRIP 242

  Fly   249 -----------VRETVELRERENIRRN----DFMDLLLDLRRQENG-----------------KG 281
                       |...:..||||....:    ||:||.||.|..:..                 |.
 Worm   243 AFKLYSIMQDVVAARIAQREREKGAESGEPQDFIDLFLDARSDDVDFSAEAREDFSKRNLKITKE 307

  Fly   282 LTMEQMAAQAFVFFVAGFETSSSNMSYALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMP 346
            |:.:::..|.|:|.:.||:|::.::||..:.||.|..:|:|:..||....|. .::.:|.:..:.
 Worm   308 LSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREFGT-SEVEFEKLGRLK 371

  Fly   347 YLDQTITETLRKYPALSSLTRLASEDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPEP-H 410
            |:|..|.|.||.|| |:|::. :.:..:..:.:|   |.:|.|..|.:...::|||||::.|. .
 Worm   372 YMDCVIKEALRLYP-LASISN-SRKCMKTTTVNG---VKIEAGVYVQMDTWSLHYDPELWGEDVK 431

  Fly   411 EFRPERFAPDACRERHPTAFLGFGDGPRNCIGLRFGRMQVKVGLITLLRRFRFSLPPGSPTQL 473
            ||:|||::.|...| |..|:|.||.|||.|||:|...|:.|:.|..||:.:.|.  .|:.|::
 Worm   432 EFKPERWSTDEPLE-HKGAYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTFE--TGNKTRI 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a16	NP_001285631.1	CYP6-like	64..489	CDD:410679	131/450 (29%)
cyp-13A2	NP_496109.1	CYP3A-like	65..508	CDD:410678	131/450 (29%)