Protein Alignment Cyp6a16 and cyp-13A5

DIOPT Version :10

• Sequence 1: NP_001285631.1
• Gene: Cyp6a16 / 19836250
• FlyBaseID: FBgn0031726
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_496112.1
• Gene: cyp-13A5 / 188356
• WormBaseID: WBGene00011672
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 147/547 - (26%)
• Similarity: 253/547 - (46%)
• Gaps: 97/547 - (17%)

  Fly     1 MDFTLLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFLFGHFFRLQSVHYSELLQ-----ETYD 60
            |..::|:..:....||.|..:.:::|..:|:...|....||.....|......||:     :.|.
 Worm     1 MSLSILIAGASFIGLLTYYIWIWSFWIRKGVKGPRGFPFFGVIHEFQDYENPGLLKLGEWTKEYG 65

  Fly    61 AFRGSAK-VAGTYVFLRPMAVVLDLDLVKAVLIRDFNNFVDRRS--FHGDP---LTANLFNLQGE 119
            ...|..: |..|.:...|       :.|..|.::.|:||..|::  ..|||   ..|:|.:.||.
 Worm    66 PIYGITEGVEKTLIVSNP-------EFVHEVFVKQFDNFYGRKTNPIQGDPNKNKRAHLVSAQGH 123

  Fly   120 EWRNLRTKLSPTFTSGKMKYMFGTVSTVAQQLGGTFDELVGSQGAVLELHDLMARYTTDVIGSCA 184
            .|:.|||..||||::..::.:..||.....:|....|: ..::|..::|.|....:|.|:||..|
 Worm   124 RWKRLRTLSSPTFSNKNLRKIMSTVEETVVELMRHLDD-ASAKGKAVDLLDYYQEFTLDIIGRIA 187

  Fly   185 FG-TECSSLREPQAEFRQVGRRIFRNSNR------------SIRWRIFKMTYLSSLAKLGLPVRI 236
            .| ||....|.|.  ..:| :.||::..:            ...:|.|.|.:.|
 Worm   188 MGQTESLMFRNPM--LPKV-KGIFKDGRKLPFLVSGIFPIAGTMFREFFMRFPS----------- 238

  Fly   237 LHP--DITKFFNRIVRETVELR---ERENIRRN----DFMDLLLDLR------RQENGKG----- 281
            :.|  ||.....:.:.:.:|.|   |:..|..:    ||:||.||.|      .:|:..|
 Worm   239 IQPAFDIMSTVEKALNKRLEQRAADEKAGIEPSGEPQDFIDLFLDARANVDFFEEESALGFAKTE 303

  Fly   282 -------LTMEQMAAQAFVFFVAGFETSSSNMSYALFELAKNQDVQQKLRMEINDSIGKHGKLTY 339
                   ||.:::..|.|||.:||::|::.::||:.:.||::.::|:||:.|: |....:.::|:
 Worm   304 IAKVDKQLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEV-DRECPNPEVTF 367

  Fly   340 EAMMEMPYLDQTITETLRKYPALSSL-TRLASEDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDP 403
            :.:.::.|::..:.|.||.||..|.: .|...::..:..      |.:||||:|.:....:||||
 Worm   368 DQISKLKYMECVVKEALRMYPLASIVHNRKCMKETNVLG------VQIEKGTNVQVDTWTLHYDP 426

  Fly   404 EVYPE-PHEFRPERFAPDACRERHPTAFLGFGDGPRNCIGLRFGRMQVKVGLITLLRRFRF---- 463
            :|:.| .:||||||:............:|.||.|||.|||:|...|:.|:.|..:|:::.|
 Worm   427 KVWGEDANEFRPERWESGDELFYAKGGYLPFGMGPRICIGMRLAMMEKKMLLTHILKKYTFETST 491

  Fly   464 --SLP---PGSPT------QLKVTKRN 479
              .:|   .||.|      .||:|.|:
 Worm   492 QTEIPLKLVGSATTAPRSVMLKLTPRH 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a16	NP_001285631.1	CYP6-like	64..489	CDD:410679	133/479 (28%)
cyp-13A5	NP_496112.1	CYP3A-like	63..511	CDD:410678	130/476 (27%)