Protein Alignment Cyp6a16 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_001285631.1
• Gene: Cyp6a16 / 19836250
• FlyBaseID: FBgn0031726
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 519
• Identity: 150/519 - (28%)
• Similarity: 250/519 - (48%)
• Gaps: 75/519 - (14%)

  Fly     5 LLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFLFGHFFRLQSVH---YSELLQETYDAFRGSA 66
            |.:|||::..|..|| :.::||:.|||.....:.:.|....:.|..   |.:|.:.|    :...
 Worm     6 LAILTSIIGVLSFYL-WTWSYWKRRGIAGPSGYPILGSALEMLSSENPPYLQLKEWT----KQYG 65

  Fly    67 KVAGTYVFLRPMAVVLDLDLVKAVLIRDFNNFVDRR--SFHGDP---LTANLFNLQGEEWRNLRT 126
            ||.|....|....|:.|.|||:.|.::.::||..|:  ...|||   ...|||:.||..|:.|||
 Worm    66 KVYGITEGLSRTLVISDPDLVQEVFVKQYDNFFGRKLNPIQGDPNKDKRVNLFSSQGHRWKRLRT 130

  Fly   127 KLSPTFTSGKMKYMFGTVSTVAQQLGGTFDELVGSQGAVLELHDLMARYTTDVIGSCAFG-TECS 190
            ..||||::..::.:..||...|.:|....::.... |..::|.|....:|.||||..|.| |:..
 Worm   131 ISSPTFSNNSLRKLKTTVEECAVELLRHIEQHTDG-GQPIDLLDFYQEFTLDVIGRIAMGQTDSQ 194

  Fly   191 SLREP-----QAEFRQVGRRIFRNSNRSIRW--RIFKMTYLSSLAKLGLPVRILHP--DITKFFN 246
            ..:.|     :|.|.:..:.:|.:.:.: .|  .|.:|...|      ||..:.:|  .:.:..:
 Worm   195 MFKNPLLPYVRAVFGEPRKGLFLSGSLA-PWIGPILRMVMFS------LPNIVKNPAVHVIRHTS 252

  Fly   247 RIVRETVELR---ERENI---RRNDFMDLLLDLRRQ----ENG-----------KGLTMEQMAAQ 290
            ..|.:.|:||   |:..|   ...||:||.||.:..    ||.           :.||.|::..|
 Worm   253 NAVEQRVKLRMADEKAGIDPGEPQDFIDLFLDAKSDDVELENNEDFTKAGVKVTRQLTTEEIVGQ 317

  Fly   291 AFVFFVAGFETSSSNMSYALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTITET 355
            .|||.:|||:|::.::||:.|.||.:..||:||:.|| |......::|::.:.::.|::..|.||
 Worm   318 CFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEI-DRECADPEVTFDQLSKLKYMECVIKET 381

  Fly   356 LRKYP--ALSS------LTRLASEDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPE-PHE 411
            ||.||  ||::      .|::.  :|||           ::||::......:|.|..::.| ..|
 Worm   382 LRMYPLGALANSRCCMRATKIG--NYEI-----------DEGTNILCDTWTLHSDKSIWGEDAEE 433

  Fly   412 FRPERFAPDACRERHPTAFLGFGDGPRNCIGLRFGRMQVKVGLITLLRRFRFSLPPGSPTQLKV 475
            |:|||:............::.||.|||.|||:|...|:.|:.|..:||::...:...:...||:
 Worm   434 FKPERWESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHILRKYTLEVCNKTQIPLKL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a16	NP_001285631.1	CYP6-like	64..489	CDD:410679	133/457 (29%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	133/457 (29%)