Protein Alignment Cyp6a16 and Cyp3a9

DIOPT Version :9

• Sequence 1: NP_001285631.1
• Gene: Cyp6a16 / 19836250
• FlyBaseID: FBgn0031726
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 511
• Identity: 169/511 - (33%)
• Similarity: 272/511 - (53%)
• Gaps: 45/511 - (8%)

  Fly     1 MDFTLLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFLFGHF--FRLQSVHYSELLQETYDAFR 63
            |:..|||:.||:...| |..:....::..|||..:|....|..  :|.....:.:...:.|
  Rat     9 METWLLLVISLVLLYL-YGTHSHGIFKKLGIPGPKPLPFLGTILAYRKGFWEFDKYCHKKY---- 68

  Fly    64 GSAKVAGTYVFLRPMAVVLDLDLVKAVLIRD-FNNFVDRRSFHGDPLTANLFNL-QGEEWRNLRT 126
              .|:.|.|...:|:..:.|.|::|.||::: ::.|.:||:|....:.....:: :.|||:.:|.
  Rat    69 --GKLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRNFGPVGILKKAISISEDEEWKRIRA 131

  Fly   127 KLSPTFTSGKMKYMFGTVSTVAQQLGGTFDELVGS-QGAVLELHDLMARYTTDVIGSCAFGTECS 190
            .|||||||||:|.||..::.....|.....:  || :|....:.|:...|:.|||.:.:||....
  Rat   132 LLSPTFTSGKLKEMFPIINQYTDMLVRNMRQ--GSEEGKPTSMKDIFGAYSMDVITATSFGVNVD 194

  Fly   191 SLREPQAEFRQVGRRIFRNSNRSIRWRIFKMTYLS-----SLAKL--GLPVRILHPDITKFFNRI 248
            ||..||..|.:..:::       :::.||...:||     .|..|  .|.|.:...|:..||...
  Rat   195 SLNNPQDPFVEKIKKL-------LKFDIFDPLFLSVTLFPFLTPLFEALNVSMFPRDVIDFFKTS 252

  Fly   249 VRETVE--LRERENIRRNDFMDLLLDLRR---QENGKGLTMEQMAAQAFVFFVAGFETSSSNMSY 308
            |....|  ::|:|. :|.||:.|:::.:.   :::.|.|:..::.||:.:|..||:||:||.:|:
  Rat   253 VERMKENRMKEKEK-QRMDFLQLMINSQNSKVKDSHKALSDVEIVAQSVIFIFAGYETTSSALSF 316

  Fly   309 ALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTITETLRKYPALSSLTRLASEDY 373
            .|:.||.:.|:|:||:.||:.::......||:.:::|.|||..:.||||.||....|.|:...|.
  Rat   317 VLYLLAIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDV 381

  Fly   374 EIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPEPHEFRPERFAPDACRERHPTAFLGFGDGPR 438
            ||      :.|.:.|||.|.||..|:|.||..:|||.|||||||:.......:|..:|.||:|||
  Rat   382 EI------NGVFIPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQDNINPYMYLPFGNGPR 440

  Fly   439 NCIGLRFGRMQVKVGLITLLRRFRFSLPPGSPTQ--LKVTKRNLILLPSDGVRLQV 492
            ||||:||..|.:||.|:.:|:.|.|.  |...||  ||::|:.| |.|...:.|:|
  Rat   441 NCIGMRFALMNMKVALVRVLQNFSFQ--PCKETQIPLKLSKQGL-LQPEKPLLLKV 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a16	NP_001285631.1	p450	32..492	CDD:278495	158/478 (33%)
Cyp3a9	NP_671739.2	p450	39..493	CDD:278495	158/478 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8924
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.870