Protein Alignment Cyp6a16 and Cyp3a62

DIOPT Version :10

• Sequence 1: NP_001285631.1
• Gene: Cyp6a16 / 19836250
• FlyBaseID: FBgn0031726
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 480
• Identity: 157/480 - (32%)
• Similarity: 248/480 - (51%)
• Gaps: 56/480 - (11%)

  Fly    12 LSFLLGYLRYRFTYWELRGIPQLRPHFLFGHFFRLQSVHYSELLQETYDAFRGSAKVAGTYVFLR 76
            |.|:...|.||..:||               |.|.....|.:              :.|.|...:
  Rat    44 LPFVGNILAYRHGFWE---------------FDRHCHKKYGD--------------IWGFYEGRQ 79

  Fly    77 PMAVVLDLDLVKAVLIRD-FNNFVDRRSFHGDPLTANLFNL-QGEEWRNLRTKLSPTFTSGKMKY 139
            |:..:.|.|::|.||::: ::.|.:||||....:......| :.|||:.|||.|||||||||:|.
  Rat    80 PILAITDPDIIKTVLVKECYSTFTNRRSFGPAGILKKAITLSEDEEWKRLRTLLSPTFTSGKLKE 144

  Fly   140 MFGTVSTVAQQLGGTFDELV------GSQGAVLELHDLMARYTTDVIGSCAFGTECSSLREPQAE 198
            ||..::..|       |.||      ..:|..:.:.|:...|:.|||...:||....||..||..
  Rat   145 MFPIINQYA-------DLLVKNVKHEAEKGNPITMKDIFGAYSMDVITGTSFGVNVDSLNNPQNP 202

  Fly   199 FRQVGRRIFR-NSNRSIRWRIFKMTYLSSLAKLGLPVRILHPDITKFFNRIVRETVELRERENIR 262
            |.|..:::.: |........:....:|:.:.: ...:.:...|:.|||...|....|.|.:|.::
  Rat   203 FVQKVKKLLKFNFLDPFFLSVILFPFLTPVFE-AFDITVFPKDVMKFFRTSVERMKENRMQEKVK 266

  Fly   263 -RNDFMDLLLDLRR---QENGKGLTMEQMAAQAFVFFVAGFETSSSNMSYALFELAKNQDVQQKL 323
             |.||:.|:::.:.   :|:.:|||..::.||:..|..||:||:||.:|:||:.||.:.|:|:||
  Rat   267 QRLDFLQLMINSQSSGDKESHQGLTDVEIVAQSIFFIFAGYETTSSALSFALYLLATHPDLQKKL 331

  Fly   324 RMEINDSIGKHGKLTYEAMMEMPYLDQTITETLRKYPALSSLTRLASEDYEIPSPDGGDPVVLEK 388
            :.||:.::.....:||:.::||.|||..:.||||.:|....|.|:..:|.||      :.|.:.|
  Rat   332 QDEIDAALPNKAPVTYDVLVEMEYLDMVLNETLRLFPVGGRLERVCKKDVEI------NGVFIPK 390

  Fly   389 GTSVHIPVLAIHYDPEVYPEPHEFRPERFAPDACRERHPTAFLGFGDGPRNCIGLRFGRMQVKVG 453
            ||.|.:|..|:|.||:.:|||.||.||||........:|..:|.||:|||||||:||..|.:|:.
  Rat   391 GTVVMVPTFALHKDPKCWPEPEEFCPERFRKKNQDSINPYIYLPFGNGPRNCIGMRFALMNMKIA 455

  Fly   454 LITLLRRFRFSLPPGSPTQLKVTKR 478
            |:.:|:.|.|.|...:...||:.|:
  Rat   456 LVRVLQNFSFGLCKETQIPLKLRKK 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a16	NP_001285631.1	CYP6-like	64..489	CDD:410679	147/428 (34%)
Cyp3a62	NP_001019403.1	CYP3A	67..492	CDD:410743	148/442 (33%)