Protein Alignment Cyp6a16 and Cyp4a12b

DIOPT Version :10

• Sequence 1: NP_001285631.1
• Gene: Cyp6a16 / 19836250
• FlyBaseID: FBgn0031726
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Alignment Length: 520
• Identity: 147/520 - (28%)
• Similarity: 241/520 - (46%)
• Gaps: 59/520 - (11%)

  Fly     6 LLLTSLLSFLLGYLR----YRFTYWEL---RGIPQLRPHFLFGHFFRLQSVHYSELLQETYDAFR 63
            |.:.|:||.||...:    |....|.|   :..|....|:||||     .:...:.||:.....:
Mouse    19 LQVASVLSLLLLLFKTAQLYLHRQWLLSSTQQFPSPPSHWLFGH-----KILKDQDLQDILTRIK 78

  Fly    64 GSAKVAGTYVFLRPMAV-VLDLDLVKAVLIRDFNNFVDRRSFHGD-----P-LTANLFNLQGEEW 121
            ........:::...:.: |.|.|.:|.:|.|.     |.:: ||.     | :...|..|.|:.|
Mouse    79 NFPSACPQWLWGSKVRIQVYDPDYMKLILGRS-----DPKA-HGSYRFLAPWIGRGLLLLDGQTW 137

  Fly   122 RNLRTKLSPTFTSGKMKYMFGTVSTVAQQLGGTFDELVGSQGAVLELHDLMARYTTDVIGSCAFG 186
            ...|..|:|.|....:|.....::.....:...::::|| |.:.||:...:...|.|.|..|||.
Mouse   138 FQHRRMLTPAFHYDILKPYTEIMADSVHVMLDKWEQIVG-QDSTLEIFQHITLMTLDTIMKCAFS 201

  Fly   187 TECSSLREPQAE-------------FRQVGRRIFRNSNRSIRWRIFKMTYLSSLAKLGLPVRILH 238
            .|.|...:.:.:             |.:| |.||..::     .|::::....||.....:...|
Mouse   202 HEGSVQLDRKYKSYIQAVEDLNNLFFLRV-RNIFHQND-----IIYRVSSNGCLANSACQLAHDH 260

  Fly   239 PD-ITKFFNRIVRETVELRERENIRRNDFMDLLLDLRRQENGKGLTMEQMAAQAFVFFVAGFETS 302
            .| :.|.....:::..||.:.:..||.||:|:|| ..|.||||.|:.:.:.|:...|...|.:|:
Mouse   261 TDQVIKSRRSQLQDEEELEKLKKKRRLDFLDILL-FARMENGKSLSDKDLRAEVDTFMFEGHDTT 324

  Fly   303 SSNMSYALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTITETLRKYPALSSLTR 367
            :|.:|:..:.||.|.:.||:.|.||...:|....:|:..:.:|||....|.|.||.||.:.|::|
Mouse   325 ASGISWIFYALATNPEHQQRCRKEIQSLLGDGASITWNDLDKMPYTTMCIKEALRIYPPVPSVSR 389

  Fly   368 LASEDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPEPHEFRPERFAPDACRERHPTAFLG 432
            ..|.  .:..|||..   |.||..|.:....:|::|.|:|.|..|.|.||||.:.|..|  :||.
Mouse   390 ELSS--PVTFPDGRS---LPKGIHVMLSFYGLHHNPTVWPNPEVFDPSRFAPGSSRHSH--SFLP 447

  Fly   433 FGDGPRNCIGLRFGRMQVKVGL-ITLLRRFRFSLPPGSPTQLKVTKRNLILLPSDGVRLQVDPVE 496
            |..|.|||||.:|...::||.: :|||   ||.|.| .||::.:....::|...:|:.|.:..::
Mouse   448 FSGGARNCIGKQFAMNELKVAVALTLL---RFELLP-DPTRVPIPIPRIVLKSKNGIHLHLKKLQ 508

  Fly   497  496
            Mouse   509  508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a16	NP_001285631.1	CYP6-like	64..489	CDD:410679	129/446 (29%)
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	131/457 (29%)