Protein Alignment Cyp6a16 and cyp3a4.1

DIOPT Version :9

• Sequence 1: NP_001285631.1
• Gene: Cyp6a16 / 19836250
• FlyBaseID: FBgn0031726
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: XP_002943949.2
• Gene: cyp3a4.1 / 100494419
• XenbaseID: XB-GENE-984218
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 518
• Identity: 164/518 - (31%)
• Similarity: 252/518 - (48%)
• Gaps: 72/518 - (13%)

  Fly     4 TLLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFLFGHFFRLQSVHYSELLQETYDAFRGSAKV 68
            |.:||..||..:|.|..:.:..::..|||...|....|.|...:    ..::|...:.|:...::
 Frog    11 TWILLAVLLVLILLYGIWPYGLFKKMGIPGPTPLPFIGTFLEFR----KGMIQFDIECFKKYGRM 71

  Fly    69 AGTYVFLRPMAVVLDLDLVKAVLIRD-FNNFVDRRSFH-GDPLTANLFNLQGEEWRNLRTKLSPT 131
            .|.|...:|:..::|..::|.:|::: :.||.:||:|. ..||.:.:...:.|:|:.:|:.||||
 Frog    72 WGMYDGRQPVLAIMDPAIIKTILVKECYTNFTNRRNFGLNGPLESAITVAEDEQWKRIRSVLSPT 136

  Fly   132 FTSGKMKYMFGTVSTVAQ------QLGGTFDELVGSQGAVLELHDLMARYTTDVIGSCAFGTECS 190
            |||||:|.||..:...:.      |:....||...::       |::..|:.|||.|.:|.....
 Frog   137 FTSGKLKEMFQIMKDYSDILVKNVQVSVDKDEPCATK-------DVIGAYSMDVITSTSFSVNID 194

  Fly   191 SLREPQAEFRQVGRRIFRNSNRSIRWRIFKMTYLSSLAKLGLPVRILHP------------DITK 243
            ||:.|...|      :....|      :.|..:||.:....:....|.|            |.|:
 Frog   195 SLQNPSNPF------VIHIKN------LLKTGFLSPVIIFAVIFPFLRPIFEVLNISFFPKDFTQ 247

  Fly   244 FFNRIVRETVELRER-ENIRRNDFMDLLLDLRRQENG------KGLTMEQMAAQAFVFFVAGFET 301
            ||...|....|.|:: ::..|.|.:.|::|....|..      |.||..::.||:.:|..||:||
 Frog   248 FFMNAVTSFREKRKKGDHSGRVDLLQLMVDSGTTEGNDSSNQHKALTDAEIMAQSLIFIFAGYET 312

  Fly   302 SSSNMSYALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTITETLRKYPALSSLT 366
            :|:.:||..:.||.:.||||||..||:..:......||:.:|:|.|||..|.||||.:|....|.
 Frog   313 TSTALSYLFYNLATHPDVQQKLHEEIDSFLPDKASPTYDILMQMEYLDMVIQETLRLFPPAGRLE 377

  Fly   367 RLASEDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPEPHEFRPERFAPDACRERHPTAFL 431
            |::.::.||      :.|.:.|||...||...:..|||.:|||.|||||||:.:....:.|..||
 Frog   378 RVSKQNVEI------NGVSIPKGTVAMIPAYVLQRDPEYWPEPEEFRPERFSKENRATQTPFTFL 436

  Fly   432 GFGDGPRNCIGLRFGRMQVKVGLITLLRRF------------RFS----LPPGSPTQLKVTKR 478
            .|||||||||||||..:.:||.:.|||:.|            .||    |.|..|..||...|
 Frog   437 PFGDGPRNCIGLRFALLSMKVAIATLLQNFSVRPCAETLIPMEFSTIGVLQPKKPIVLKFLSR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a16	NP_001285631.1	p450	32..492	CDD:278495	155/490 (32%)
cyp3a4.1	XP_002943949.2	p450	39..496	CDD:365848	153/485 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	239	1.000	Domainoid score	I2234
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3174
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.060