DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG44250 and CG10916

DIOPT Version :9

Sequence 1:	NP_001163133.1	Gene:	CG44250 / 19836034	FlyBaseID:	FBgn0265185	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001261070.1	Gene:	CG10916 / 37081	FlyBaseID:	FBgn0034312	Length:	263	Species:	Drosophila melanogaster

Alignment Length:	159	Identity:	65/159 - (40%)
Similarity:	86/159 - (54%)	Gaps:	12/159 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VTVDNTWV------HSSPYSPLPPY-AVIGGHDSDRTPIYVGRSFHEGENLPAKVVPSKGCAYVA 67
            |.:|  ||      .|.|.:.|||. ||..|.:.|..|.||.|.::..:.|||..||.|..|:.:
  Fly   103 VAMD--WVPIDLDRDSLPDAHLPPEGAVQCGTNEDGLPTYVARGYYHDDLLPAPYVPEKKAAFGS 165

  Fly    68 YGGAEHTKT-HYEVLV--GQGFAWVPSSSGGVPPNAVRSGTTRTGEPLYVGRGHHAGSLTVGKVH 129
            :..:..|.| ..|:||  ...:.|||...|..|.:|:.:|.:..||..|.|||.:.|.|.:||||
  Fly   166 HSCSARTLTDDVEILVLNDCDYKWVPGQHGTYPRDALNTGYSELGEVTYTGRGLYQGILRLGKVH 230

  Fly   130 PSHGCLYIPFGGQEVRINTYEVLIKQQHD 158
            |||..:|||..||||.:||||||:....|
  Fly   231 PSHKVMYIPHHGQEVSVNTYEVLVVTPRD 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44250	NP_001163133.1	DM9	13..84	CDD:128937	28/80 (35%)
		DUF3421	35..145	CDD:288732	45/112 (40%)
		DM9	85..155	CDD:128937	35/69 (51%)
		DM9	157..227	CDD:128937	1/2 (50%)
		DUF3421	178..287	CDD:288732
		DM9	228..297	CDD:128937
CG10916	NP_001261070.1	zf-RING_2	32..74	CDD:290367
		zf-rbx1	<32..74	CDD:289448
		DM9	105..183	CDD:128937	28/79 (35%)
		DUF3421	133..246	CDD:288732	45/112 (40%)
		DM9	186..254	CDD:128937	34/67 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449322
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005929
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR31649
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940