DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44250 and AgaP_AGAP009606

DIOPT Version :9

Sequence 1:	NP_001163133.1	Gene:	CG44250 / 19836034	FlyBaseID:	FBgn0265185	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	XP_318634.4	Gene:	AgaP_AGAP009606 / 1278979	VectorBaseID:	AGAP009606	Length:	297	Species:	Anopheles gambiae

Alignment Length:	285	Identity:	90/285 - (31%)
Similarity:	140/285 - (49%)	Gaps:	13/285 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 WVHSSPYSPLPPYAVIGGHDSDRTPIYVGRSFHEGENLPAKVVPSKGCAYVAYGGAEHTKTHYEV 80
            ||.::. ..:||.||:.|::.:.|  |:||:.|....:|.:|:|||....:...|.||....|:|
Mosquito     5 WVLAAE-GVVPPEAVVAGYEGETT--YIGRAKHRKAIVPGRVIPSKKACLIVSEGLEHAVHDYQV 66

  Fly    81 LVGQGFAWVPSSSGGVPPNAVRSGTTRTGEPLYVGRGHHAGSLTVGKVHPSHGCLYIPFGGQEVR 145
            |.|....:|.:|.|..|..:::.|.|:.|:|:::|.........||.:.|...|......|...|
Mosquito    67 LCGYDGRFVQTSGGYCPIGSLQGGVTKRGKPIFIGLVRMGLVTVVGSIVPDEFCCQAVVNGILRR 131

  Fly   146 INTYEVLIKQQHDV-----WVPASPSYTPPGAVIAGHDSDRTPIYAGRAMHEGEMLPAKVVPSKG 205
            .|.||:....:|..     ||.|:....||.||:.|::.:.|  :.|||.|.|.::|.::||||.
Mosquito   132 FNDYEIFGYTEHAYLDNARWVQAAEGLVPPDAVVGGYEGEVT--FIGRAKHRGSIVPGRIVPSKK 194

  Fly   206 TAYVCFGGYEFQKPSYEVLTGY--GYVWMNCGHSIPPNAVTTGRARNGELLYYGRGHYQGSLTPG 268
            ...|.:||.|..|..|:||.||  .:|.:..|: ||..|:..|.:.:|:.||.|......:...|
Mosquito   195 ACCVVWGGEEHTKSDYQVLCGYEGHFVHVGGGY-IPNGALRGGVSEHGKPLYIGLVRLGSTTVVG 258

  Fly   269 LISASQRCLYIPYGGREIRINSYEI 293
            .:.....|.||..||.|.....|::
Mosquito   259 KVQPEHSCCYIAVGGVEKAFREYDV 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44250	NP_001163133.1	DM9	13..84	CDD:128937	23/67 (34%)
		DUF3421	35..145	CDD:288732	31/109 (28%)
		DM9	85..155	CDD:128937	18/69 (26%)
		DM9	157..227	CDD:128937	28/74 (38%)
		DUF3421	178..287	CDD:288732	38/110 (35%)
		DM9	228..297	CDD:128937	18/66 (27%)
AgaP_AGAP009606	XP_318634.4	DM9	5..70	CDD:128937	23/67 (34%)
		DUF3421	22..127	CDD:288732	30/106 (28%)
		DM9	151..216	CDD:128937	27/66 (41%)
		DUF3421	168..275	CDD:288732	37/109 (34%)
		DM9	217..285	CDD:128937	18/68 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154851at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920