DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44250 and AgaP_AGAP006398

DIOPT Version :9

Sequence 1:	NP_001163133.1	Gene:	CG44250 / 19836034	FlyBaseID:	FBgn0265185	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	XP_316431.3	Gene:	AgaP_AGAP006398 / 1277009	VectorBaseID:	AGAP006398	Length:	290	Species:	Anopheles gambiae

Alignment Length:	281	Identity:	163/281 - (58%)
Similarity:	196/281 - (69%)	Gaps:	2/281 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 WVHSSPYSPLPPYAVIGGHDSDRTPIYVGRSFHEGENLPAKVVPSKGCAYVAYGGAEHTKTHYEV 80
            |:..:.:..:||.||.||:|.|.:|||:||::|||:.|||||:|||..|||::.|.|..|||:||
Mosquito     7 WIPWTSHQGIPPAAVYGGNDQDGSPIYIGRAYHEGDQLPAKVIPSKQAAYVSHNGMEIFKTHFEV 71

  Fly    81 LVGQGFAWVPSSSGGVPPNAVRSGTTRTGEPLYVGRGHHAGSLTVGKVHPSHGCLYIPFGGQEVR 145
            |.|.||.||.|.:|.||.|||.:|.|.|||.||:||.||.||||.||:|.|||||||||||.|..
Mosquito    72 LTGTGFTWVSSGNGHVPANAVLAGNTTTGEQLYIGRTHHEGSLTPGKIHRSHGCLYIPFGGAEQS 136

  Fly   146 INTYEVLIKQQHDVWVPASP-SYTPPGAVIAGHDSDRTPIYAGRAMHEGEMLPAKVVPSKGTAYV 209
            ..:||||:.||...|...|. :..||.||:||:|||.:|||.||..|||:.|||||:|||..|||
Mosquito   137 FLSYEVLVGQQRSNWQHCSAHAPMPPNAVLAGNDSDGSPIYVGRTYHEGDQLPAKVLPSKQIAYV 201

  Fly   210 CFGGYEFQKPSYEVLTGYGYVWMNCGH-SIPPNAVTTGRARNGELLYYGRGHYQGSLTPGLISAS 273
            |..|.|..|.|:|||||....|:..|. |:|||||..||..:||.||.||.||.||||||.|..|
Mosquito   202 CHNGQEIPKHSFEVLTGGQVSWVPSGFGSVPPNAVFGGRTSSGEALYIGRAHYMGSLTPGKIHPS 266

  Fly   274 QRCLYIPYGGREIRINSYEIL 294
            .:.|||||||.||.|.:||:|
Mosquito   267 HQTLYIPYGGSEIPIKNYEVL 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44250	NP_001163133.1	DM9	13..84	CDD:128937	36/67 (54%)
		DUF3421	35..145	CDD:288732	71/109 (65%)
		DM9	85..155	CDD:128937	45/69 (65%)
		DM9	157..227	CDD:128937	39/70 (56%)
		DUF3421	178..287	CDD:288732	66/109 (61%)
		DM9	228..297	CDD:128937	39/68 (57%)
AgaP_AGAP006398	XP_316431.3	DM9	4..75	CDD:128937	36/67 (54%)
		DUF3421	26..136	CDD:288732	71/109 (65%)
		DM9	76..146	CDD:128937	45/69 (65%)
		DM9	151..219	CDD:128937	39/67 (58%)
		DUF3421	170..279	CDD:288732	65/108 (60%)
		DM9	222..288	CDD:128937	39/66 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I8452
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	332	1.000	Inparanoid score	I4708
OMA	1	1.010	-	-		QHG26584
OrthoDB	1	1.010	-	-		D106292at50557
OrthoFinder	1	1.000	-	-		FOG0005929
OrthoInspector	1	1.000	-	-		otm50145
Panther	1	1.100	-	-	LDO	PTHR31649
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X15945
TreeFam	0	0.000	Not matched by this tool.
	10	10.080