DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44271 and Rnf4

DIOPT Version :9

Sequence 1:	NP_001285689.1	Gene:	CG44271 / 19835868	FlyBaseID:	FBgn0265257	Length:	106	Species:	Drosophila melanogaster
Sequence 2:	NP_062055.1	Gene:	Rnf4 / 29274	RGDID:	3583	Length:	194	Species:	Rattus norvegicus

Alignment Length:	106	Identity:	29/106 - (27%)
Similarity:	43/106 - (40%)	Gaps:	35/106 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RRAGDGMKT--LETVDLTTDDEERPVLRLLSD---------------------RNNGHYLCPICM 61
            ||.|..::.  .::..:::||||     |..|                     |.:|...|||||
  Rat    81 RRNGRRLRQDHADSCVVSSDDEE-----LSKDKDVYVTTHTPRSTKDEGTTGLRPSGTVSCPICM 140

  Fly    62 SLPDH-------PVATTCGHIFCKECLTTALNQLHYCPLCK 95
            .....       .|:|.|||:||.:||..:|...:.||.|:
  Rat   141 DGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCR 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44271	NP_001285689.1	RING	57..95	CDD:238093	17/44 (39%)
Rnf4	NP_062055.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..36
		Required for ubiquitination activity. /evidence=ECO:0000250	1..20
		Mediates interaction with TRPS1. /evidence=ECO:0000250	6..65
		SUMO interaction motif 1. /evidence=ECO:0000269\|PubMed:18408734	40..43
		SUMO interaction motif 2. /evidence=ECO:0000269\|PubMed:18408734	50..53
		SUMO interaction motif 3. /evidence=ECO:0000269\|PubMed:18408734	61..63
		SUMO interaction motif 4. /evidence=ECO:0000269\|PubMed:18408734	71..74
		RING-HC_RNF4	131..184	CDD:319447	19/51 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	51	1.000	Domainoid score	I11266
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001208
OrthoInspector	1	1.000	-	-		otm45623
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910