DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44247 and Npdc1

DIOPT Version :9

Sequence 1:	NP_611974.2	Gene:	CG44247 / 19835727	FlyBaseID:	FBgn0265182	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_032747.2	Gene:	Npdc1 / 18146	MGIID:	1099802	Length:	332	Species:	Mus musculus

Alignment Length:	298	Identity:	93/298 - (31%)
Similarity:	131/298 - (43%)	Gaps:	61/298 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 AVGP------SDARFFDNPND--PSGE-LDSRALEDYEEYAPIEPTTEVATTASKTKIDTPVPAP 240
            |.||      .|.|.|..|..  .||| |....||  ||...:  ..|:|....:.........|
Mouse    62 ACGPCLQSFQEDQRGFCVPRKHLSSGEGLPQPRLE--EEIDSL--AQELALKEKEAGHSRLTAQP 122

  Fly   241 VPVEPPKLLD-AANTNF----HRINP----QSAAAAAVAGVNIPQSKEQPPHELNALINKLQKQS 296
            :.....|||: ||...|    .|:.|    ....::.:...::.......|.::    :.|:.|.
Mouse   123 LLEAAQKLLEPAATLGFSQWGQRLEPGLPSTHGTSSPIPHTSLSSRASSGPVQM----SPLEPQG 183

  Fly   297 KAPSHLTLVNGGDSSQEQIVLRQHLGMNSEMGVYIVALIAGVSAAVTVGLLALGVTWFHNRHK-- 359
            :..:.|||                        |.|:|.....|||:.|..|.    |...:.:
Mouse   184 RHGNGLTL------------------------VLILAFCLASSAALAVAALC----WCRLQREIR 220

  Fly   360 --AAADVEYPAYGVTGPNKD-VSPSGDRKLAQSAQMYHYQHQKQQIIAMENQATDGSCGMSDVES 421
              ..||....|.|.|.|:.. :|| ||::||.||:|||||||:||::.:|.. .:....:....|
Mouse   221 LTQKADYAATAKGPTSPSTPRISP-GDQRLAHSAEMYHYQHQRQQMLCLERH-KEPPKELESASS 283

  Fly   422 DDDNEEGDYTVYECPGLAPTGEMEVKNPLFLDETPATP 459
            |::||:||:||||||||||||||||:||||...|.:.|
Mouse   284 DEENEDGDFTVYECPGLAPTGEMEVRNPLFDHSTLSAP 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44247	NP_611974.2	NPDC1	<329..459	CDD:284276	60/134 (45%)
Npdc1	NP_032747.2	NPDC1	1..332	CDD:284276	93/298 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	145..182		4/40 (10%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	272..300		12/27 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	312..332		4/10 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850819
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004167
OrthoInspector	1	1.000	-	-		oto94477
orthoMCL	1	0.900	-	-		OOG6_108176
Panther	1	1.100	-	-	LDO	PTHR23352
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5781
SonicParanoid	1	1.000	-	-		X3987
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.870