Protein Alignment CG44247 and Npdc1

DIOPT Version :10

• Sequence 1: NP_611974.2
• Gene: CG44247 / 19835727
• FlyBaseID: FBgn0265182
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_032747.2
• Gene: Npdc1 / 18146
• MGIID: 1099802
• Length: 332
• Species: Mus musculus
• Alignment Length: 298
• Identity: 93/298 - (31%)
• Similarity: 131/298 - (43%)
• Gaps: 61/298 - (20%)

  Fly   185 AVGP------SDARFFDNPND--PSGE-LDSRALEDYEEYAPIEPTTEVATTASKTKIDTPVPAP 240
            |.||      .|.|.|..|..  .||| |....||  ||...:  ..|:|....:.........|
Mouse    62 ACGPCLQSFQEDQRGFCVPRKHLSSGEGLPQPRLE--EEIDSL--AQELALKEKEAGHSRLTAQP 122

  Fly   241 VPVEPPKLLD-AANTNF----HRINP----QSAAAAAVAGVNIPQSKEQPPHELNALINKLQKQS 296
            :.....|||: ||...|    .|:.|    ....::.:...::.......|.::    :.|:.|.
Mouse   123 LLEAAQKLLEPAATLGFSQWGQRLEPGLPSTHGTSSPIPHTSLSSRASSGPVQM----SPLEPQG 183

  Fly   297 KAPSHLTLVNGGDSSQEQIVLRQHLGMNSEMGVYIVALIAGVSAAVTVGLLALGVTWFHNRHK-- 359
            :..:.|||                        |.|:|.....|||:.|..|.    |...:.:
Mouse   184 RHGNGLTL------------------------VLILAFCLASSAALAVAALC----WCRLQREIR 220

  Fly   360 --AAADVEYPAYGVTGPNKD-VSPSGDRKLAQSAQMYHYQHQKQQIIAMENQATDGSCGMSDVES 421
              ..||....|.|.|.|:.. :|| ||::||.||:|||||||:||::.:|.. .:....:....|
Mouse   221 LTQKADYAATAKGPTSPSTPRISP-GDQRLAHSAEMYHYQHQRQQMLCLERH-KEPPKELESASS 283

  Fly   422 DDDNEEGDYTVYECPGLAPTGEMEVKNPLFLDETPATP 459
            |::||:||:||||||||||||||||:||||...|.:.|
Mouse   284 DEENEDGDFTVYECPGLAPTGEMEVRNPLFDHSTLSAP 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44247	NP_611974.2	Caldesmon	<34..>109	CDD:460421
		NPDC1	<329..459	CDD:284276	60/134 (45%)
Npdc1	NP_032747.2	NPDC1	1..332	CDD:284276	93/298 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..182		4/40 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	272..300		12/27 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..332		4/10 (40%)