DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and CCC2

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_010556.1	Gene:	CCC2 / 851862	SGDID:	S000002678	Length:	1004	Species:	Saccharomyces cerevisiae

Alignment Length:	203	Identity:	41/203 - (20%)
Similarity:	80/203 - (39%)	Gaps:	64/203 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 VLPL--PTKLELRPWIFLKSCF-------SILGIIILLSSIASFAMYYLF-----ATKTPDNGKV 131
            ::|:  ||.::.|.:.:.::.|       .|||:|  |:|...|::.:.|     |:....:|.:
Yeast   274 IVPMMWPTIVQDRIFPYKETSFVRGLFYRDILGVI--LASYIQFSVGFYFYKAAWASLKHGSGTM 336

  Fly   132 D-------------------------------PEFLVAGIILLVTFFLAGLTVQ-MQGDDDEDML 164
            |                               |..:....|:::::...|..:: :........|
Yeast   337 DTLVCVSTTCAYTFSVFSLVHNMFHPSSTGKLPRIVFDTSIMIISYISIGKYLETLAKSQTSTAL 401

  Fly   165 IAFDELMPMYCTVIRDGEK--------EVIRTQDLVPGDTLPIKYGQRLPADMRFFSTTG-LELN 220
            ....:|.|..|::|.|.|:        |:::..|:|     .||.|.::|||  ...|.| .|::
Yeast   402 SKLIQLTPSVCSIISDVERNETKEIPIELLQVNDIV-----EIKPGMKIPAD--GIITRGESEID 459

  Fly   221 NVALTGHS 228
            ...:||.|
Yeast   460 ESLMTGES 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	12/44 (27%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	24/99 (24%)
CCC2	NP_010556.1	HMA	6..67	CDD:238219
		HMA	84..144	CDD:238219
		P-type_ATPase_Cu-like	259..938	CDD:319783	41/203 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341381
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930