Protein Alignment CG45063 and Atp2c2

DIOPT Version :10

• Sequence 1: NP_001286728.1
• Gene: CG45063 / 19835490
• FlyBaseID: FBgn0266433
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_081198.1
• Gene: Atp2c2 / 69047
• MGIID: 1916297
• Length: 944
• Species: Mus musculus
• Alignment Length: 197
• Identity: 52/197 - (26%)
• Similarity: 87/197 - (44%)
• Gaps: 31/197 - (15%)

  Fly    52 ELCARLEANVSQGLTSEAAGRKLARNG------KNVLPLPTKLELRPWIFLKSCFSILGIIILLS 110
            ||......::..||:..|..::...:|      .|..|:..|       :|....:.|.:::|.|
Mouse    62 ELARAFHVDLDSGLSEFAVAQRRLVHGWNEFVTDNAEPVWKK-------YLDQFRNPLILLLLGS 119

  Fly   111 SIASFAMYYLFATKTPDNGKVDPEFLVAGIILLVTFFLAGLTVQMQGDDDEDMLIAFDELMPMYC 175
            |:.|      ..||..:    |...:...::::||   .|.   :|....|..|....:|:|..|
Mouse   120 SVVS------VLTKEYE----DAVSIALAVLIVVT---VGF---IQEYRSEKSLEELTKLVPPEC 168

  Fly   176 TVIRDGEKEVIRTQDLVPGDTLPIKYGQRLPADMRFFSTTGLELNNVALTGHSKPMHIT--PLAN 238
            ..:|||:...:..:||||||.:.:..|.|:|||:|....|.|.::..:.||..:|...|  |||:
Mouse   169 NCLRDGKLRHMLARDLVPGDIVSLSMGDRIPADIRLTEVTDLLVDESSFTGEVEPCGKTDSPLAD 233

  Fly   239 EG 240
            .|
Mouse   234 GG 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	ATPase-IIC_X-K	21..>230	CDD:273445	46/183 (25%)
Atp2c2	NP_081198.1	Interaction with ORAI1. /evidence=ECO:0000250|UniProtKB:O75185	69..93		4/23 (17%)
		P-type_ATPase_SPCA	83..925	CDD:319779	47/176 (27%)