DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and JYalpha

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001104092.2	Gene:	JYalpha / 5740846	FlyBaseID:	FBgn0267363	Length:	1009	Species:	Drosophila melanogaster

Alignment Length:	245	Identity:	75/245 - (30%)
Similarity:	117/245 - (47%)	Gaps:	43/245 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RKKKEERESLQ---QTENELWLEYFSPYLHIWPFHELCARLEANVSQGLTSEAAGRKLARNGKNV 81
            ::||::.:|.:   :|:|           |..|..||..||:.:.:.||:...|..:|..||.|:
  Fly    15 KEKKKDIQSFKKDVETDN-----------HKIPVDELLERLKTDPNMGLSFVEAKLRLEINGPNI 68

  Fly    82 L----PLPTKLELRPWI-FLKSCFSILGIIILLSSIASFAMYYLFATKT----PDNGKVDPEFLV 137
            |    |.|      .|| |||:.|....|::...|...| :.||...:|    ||:.      |.
  Fly    69 LTPQPPTP------KWIVFLKTMFGGFAILLWAGSFLCF-VGYLIQLQTQHEPPDDN------LY 120

  Fly   138 AGIILLVTFFLAGLTVQMQGDDDEDMLIAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIKYG 202
            .||.|.|...:.||....|......::.:|..|:|.|.||||:||...:.:.::|.||.:.:|:|
  Fly   121 LGIALTVLVIVTGLFTYFQVHKSSSIMDSFKNLVPQYATVIREGEINTVTSDEIVKGDIVEVKFG 185

  Fly   203 QRLPADMRFFSTTGLELNNVALTGHSKPM-------HITPLANEGRQRYS 245
            .|:|||:|.....||:::|.:|||.|:|.       |..||..:....:|
  Fly   186 DRVPADIRILEAHGLKVDNSSLTGESEPQVRSTEFTHENPLETKNLAFFS 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	25/75 (33%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	33/89 (37%)
JYalpha	NP_001104092.2	ATPase-IIC_X-K	17..1009	CDD:273445	75/243 (31%)
		Cation_ATPase_N	29..102	CDD:214842	27/90 (30%)
		E1-E2_ATPase	123..354	CDD:278548	38/113 (34%)
		Cation_ATPase	416..509	CDD:289987
		COG4087	<673..738	CDD:226572
		Cation_ATPase_C	785..994	CDD:279079
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438580
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S851
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.790