DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and atp13a2

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001073506.1	Gene:	atp13a2 / 568666	ZFINID:	ZDB-GENE-061215-126	Length:	1170	Species:	Danio rerio

Alignment Length:	262	Identity:	62/262 - (23%)
Similarity:	102/262 - (38%)	Gaps:	72/262 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 KKEERESLQ-QTENELWLEY--FSPYLHIWPFHE-------------LCARLEANVSQGLTSEAA 70
            :.|.|:::| .:|.:..|.|  |....:||...:             .||.|... .|||:....
Zfish   124 ENEWRDTVQLHSEKKTLLRYYVFEGIRYIWISKKGAFCKASVLSEGWTCADLHGQ-QQGLSRADQ 187

  Fly    71 GRKLARNGKNVLPLPTKLELR--------PWIFLKSCFSILGIIILLSSIASFAMYYLFATKTPD 127
            ..:....|.|::.:|.|..|:        |:..    |.:..||:.:|   ...:||
Zfish   188 STRKQIFGANIIDVPVKSYLQLLFEEVLNPFYI----FQVFSIILWMS---DGYVYY-------- 237

  Fly   128 NGKVDPEFLVAGIILLVTFFLAGLTVQMQGDDDEDMLIAFDELMPMYC-----TVIRD-GEKEVI 186
                      |..|.:::....|:::.......       ..|..|.|     ||.|| ||:|.:
Zfish   238 ----------AACIFIISLISIGVSLYETRKQS-------TTLRRMACLIVNVTVRRDTGEEECV 285

  Fly   187 RTQDLVPGDTLPI-KYGQRLPADMRFFSTTGLELNNVALTGHSKPMHITPLAN-------EGRQR 243
            .:::|||||.:.| ..|..||.|....:...: :|...|||.|.|:..|||:|       |.::|
Zfish   286 SSEELVPGDCVVIPAEGLLLPCDAALVAGECM-VNESMLTGESIPVMKTPLSNSEATYNPESQRR 349

  Fly   244 YS 245
            ::
Zfish   350 HT 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	18/91 (20%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	27/96 (28%)
atp13a2	NP_001073506.1	P5-ATPase	36..152	CDD:289194	7/27 (26%)
		P-ATPase-V	42..1102	CDD:273738	62/262 (24%)
		Cation_ATPase_N	<179..229	CDD:279080	12/53 (23%)
		E1-E2_ATPase	241..478	CDD:278548	34/119 (29%)
		Cation_ATPase	<606..646	CDD:289987
		HAD_like	<832..885	CDD:304363
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573937
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930