DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and atp2b2

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001116710.1	Gene:	atp2b2 / 557430	ZFINID:	ZDB-GENE-061016-1	Length:	1253	Species:	Danio rerio

Alignment Length:	221	Identity:	50/221 - (22%)
Similarity:	87/221 - (39%)	Gaps:	55/221 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LCARLEANVSQGLTSEAAGRKLARN--GKNVLPLPTKLELRPWIFLKSCFSIL-GIIILLSSIAS 114
            ||.||:.:.::||...|......:.  |:|::| |.|    |..||:..:..| .:.:::..||:
Zfish    53 LCQRLKTSPTEGLAGLATDLDKRKEVFGRNLIP-PKK----PKTFLQLVWEALQDVTLIILEIAA 112

  Fly   115 FAMYYLFATKTPDNGKVD----------------------PEFLVAGI-ILLVTFF--------L 148
            .....|...:.|..|..|                      ...|::.: ::|||.|        .
Zfish   113 LISLGLSFYQPPGEGNTDACGDAKAGAEDEGESEAGWIEGAAILLSVVCVVLVTAFNDWSKEKQF 177

  Fly   149 AGLTVQMQGDDDEDMLIAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIKYGQRLPADMRFFS 213
            .||..:::.:..              ..|:|.|:...:...|::.||...||||..||||.....
Zfish   178 RGLQSRIEQEQK--------------FQVVRGGQVIQLPVADILVGDIAQIKYGDLLPADGVLIQ 228

  Fly   214 TTGLELNNVALTGHSKPMHITPLANE 239
            ...|:::..:|||.|.  |:...|::
Zfish   229 GNDLKIDESSLTGESD--HVRKAADK 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	18/66 (27%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	25/98 (26%)
atp2b2	NP_001116710.1	ATPase-IIB_Ca	9..1096	CDD:273668	50/221 (23%)
		Cation_ATPase_N	48..115	CDD:279080	18/66 (27%)
		E1-E2_ATPase	191..499	CDD:278548	21/64 (33%)
		Cation_ATPase	560..649	CDD:289987
		HAD	657..840	CDD:289480
		Cation_ATPase_C	914..1092	CDD:279079
		ATP_Ca_trans_C	1137..1184	CDD:289209
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573917
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930