DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG45063 and ATP2A1

DIOPT Version :9

Sequence 1:NP_001286728.1 Gene:CG45063 / 19835490 FlyBaseID:FBgn0266433 Length:252 Species:Drosophila melanogaster
Sequence 2:NP_775293.1 Gene:ATP2A1 / 487 HGNCID:811 Length:1001 Species:Homo sapiens


Alignment Length:209 Identity:53/209 - (25%)
Similarity:97/209 - (46%) Gaps:20/209 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 HIWPFHELCARLEANVSQGLTSEAAGRKLARNGKNVLPLPTKLELRPW-IFLKSCFSILGIIILL 109
            |.....|..|....:.:.|||.:...|.|.:.|.|.||......|  | :.::....:|..|:||
Human     5 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTL--WELVIEQFEDLLVRILLL 67

  Fly   110 SSIASFAMYYLFATKTPDNGKVDPEFLVAGIILLVTFFLAGLTVQMQGDDDEDMLIAFDELMPMY 174
            ::..||.:.:....:......|:| |::  :::|:...:.|:   .|..:.|:.:.|..|..|..
Human    68 AACISFVLAWFEEGEETITAFVEP-FVI--LLILIANAIVGV---WQERNAENAIEALKEYEPEM 126

  Fly   175 CTVIRDGEKEV--IRTQDLVPGDTLPIKYGQRLPADMRFFS--TTGLELNNVALTG-------HS 228
            ..|.|...|.|  |:.:|:||||.:.:..|.::|||:|..:  :|.|.::...|||       |:
Human   127 GKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHT 191

  Fly   229 KPMHITPLANEGRQ 242
            :|:......|:.::
Human   192 EPVPDPRAVNQDKK 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG45063NP_001286728.1 Cation_ATPase_N 46..117 CDD:214842 20/71 (28%)
E1-E2_ATPase 140..>230 CDD:278548 28/100 (28%)
ATP2A1NP_775293.1 Cation_ATPase_N 4..72 CDD:279080 18/68 (26%)
ATPase-IIA1_Ca 53..989 CDD:273452 39/159 (25%)
E1-E2_ATPase 93..340 CDD:278548 30/118 (25%)
Cation_ATPase 419..528 CDD:289987
HAD <611..712 CDD:289480
Cation_ATPase_C 784..987 CDD:279079
Interaction with PLN. /evidence=ECO:0000250|UniProtKB:P04191 788..808
Interaction with PLN. /evidence=ECO:0000250|UniProtKB:P04191 932..943
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165141074
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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