Protein Alignment CG45063 and ATP1A2

DIOPT Version :9

• Sequence 1: NP_001286728.1
• Gene: CG45063 / 19835490
• FlyBaseID: FBgn0266433
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_000693.1
• Gene: ATP1A2 / 477
• HGNCID: 800
• Length: 1020
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 66/219 - (30%)
• Similarity: 113/219 - (51%)
• Gaps: 17/219 - (7%)

  Fly    21 KKKEERESLQQTENELWLEYFSPYLHIWPFHELCARLEANVSQGLTSEAAGRKLARNGKNVL-PL 84
            |||::.:.|.:.:.|:.::.     |.....||..:.:.::|:|||::.|...|||:|.|.| |.
Human    22 KKKQKEKELDELKKEVAMDD-----HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPP 81

  Fly    85 PTKLELRPWI-FLKSCFSILGIIILLSSIASFAMYYLFAT--KTPDNGKVDPEFLVAGIILLVTF 146
            ||..|   |: |.:..|....|::.:.:|..|..|.:.|.  ..|.|     :.|..|::|....
Human    82 PTTPE---WVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSN-----DNLYLGVVLAAVV 138

  Fly   147 FLAGLTVQMQGDDDEDMLIAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIKYGQRLPADMRF 211
            .:.|.....|......::.:|..::|....|||:|||..|..:::|.||.:.:|.|.|:|||:|.
Human   139 IVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRI 203

  Fly   212 FSTTGLELNNVALTGHSKPMHITP 235
            .|:.|.:::|.:|||.|:|...:|
Human   204 ISSHGCKVDNSSLTGESEPQTRSP 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	24/72 (33%)
		E1-E2_ATPase	140..>230	CDD:278548	29/89 (33%)
ATP1A2	NP_000693.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		3/8 (38%)
		ATPase-IIC_X-K	30..1020	CDD:273445	63/211 (30%)
		Interaction with phosphoinositide-3 kinase. /evidence=ECO:0000250	80..82		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..231		7/16 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141046
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840