Protein Alignment CG45063 and ATP1A1

DIOPT Version :9

• Sequence 1: NP_001286728.1
• Gene: CG45063 / 19835490
• FlyBaseID: FBgn0266433
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_000692.2
• Gene: ATP1A1 / 476
• HGNCID: 799
• Length: 1023
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 68/225 - (30%)
• Similarity: 114/225 - (50%)
• Gaps: 19/225 - (8%)

  Fly    20 RKKKEERESLQQTENELWLEYFSPYLHIWPFHELCARLEANVSQGLTSEAAGRKLARNGKNVL-P 83
            :|.|::|: :.:.:.|:.::.     |.....||..:...::|:||||..|...|||:|.|.| |
Human    24 KKGKKDRD-MDELKKEVSMDD-----HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTP 82

  Fly    84 LPTKLELRPWI-FLKSCFSILGIIILLSSIASFAMYYLFAT--KTPDNGKVDPEFLVAGIILLVT 145
            .||..|   || |.:..|....:::.:.:|..|..|.:.|.  :.|.|     :.|..|::|...
Human    83 PPTTPE---WIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQN-----DNLYLGVVLSAV 139

  Fly   146 FFLAGLTVQMQGDDDEDMLIAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIKYGQRLPADMR 210
            ..:.|.....|......::.:|..::|....|||:|||..|..:::|.||.:.:|.|.|:|||:|
Human   140 VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLR 204

  Fly   211 FFSTTGLELNNVALTGHSKPMHITP-LANE 239
            ..|..|.:::|.:|||.|:|...:| ..||
Human   205 IISANGCKVDNSSLTGESEPQTRSPDFTNE 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	25/72 (35%)
		E1-E2_ATPase	140..>230	CDD:278548	29/89 (33%)
ATP1A1	NP_000692.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..39		3/15 (20%)
		ATPase-IIC_X-K	30..1023	CDD:273445	66/219 (30%)
		Phosphoinositide-3 kinase binding. /evidence=ECO:0000250	82..84		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..235		8/19 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S851
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.860