DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and atp2b3a

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	XP_005166875.1	Gene:	atp2b3a / 436745	ZFINID:	ZDB-GENE-040718-174	Length:	1299	Species:	Danio rerio

Alignment Length:	205	Identity:	50/205 - (24%)
Similarity:	82/205 - (40%)	Gaps:	44/205 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LCARLEANVSQGLTSEAAGRKLARN--GKNVLPLP----TKLELRPWIFLKSCFSILGIIILLSS 111
            ||.||:.:.:.||:...|..:..|.  |.|.:| |    |.||| .|..|:   .|..||:.:::
Zfish    59 LCHRLKTSPADGLSDNPADLEKRRKVFGMNFIP-PKQPKTFLEL-VWEALQ---DITLIILEIAA 118

  Fly   112 IASFAMYYL------------FATKTPDNGKVDPEFLVAGIILLVTFFLAGLTV----------- 153
            |.|..:.:.            .:....|.|:.|..::....|||....:..:|.
Zfish   119 IISLGLSFYQPPGGDSEACVEVSEGAEDEGEADANWIEGAAILLSVICVVLVTAFNDWSKEKQFR 183

  Fly   154 QMQGDDDEDMLIAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIKYGQRLPADMRFFSTTGLE 218
            .:|...:::...|          |:|:.....|...::|.||...:|||..||||........|:
Zfish   184 GLQSRIEQEQRFA----------VVRNSTVIQIPVAEMVVGDIAQVKYGDLLPADGVLIQGNDLK 238

  Fly   219 LNNVALTGHS 228
            ::..:|||.|
Zfish   239 IDESSLTGES 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	23/69 (33%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	24/100 (24%)
atp2b3a	XP_005166875.1	ATPase-IIB_Ca	23..1082	CDD:273668	50/205 (24%)
		Cation_ATPase_N	57..116	CDD:279080	21/61 (34%)
		E1-E2_ATPase	164..484	CDD:278548	21/95 (22%)
		Cation_ATPase	545..634	CDD:289987
		HAD	627..825	CDD:289480
		Cation_ATPase_C	899..1077	CDD:279079
		ATP_Ca_trans_C	1122..1198	CDD:289209
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573941
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930