DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and atp2a2a

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	XP_005166855.1	Gene:	atp2a2a / 393940	ZFINID:	ZDB-GENE-040426-702	Length:	1042	Species:	Danio rerio

Alignment Length:	198	Identity:	52/198 - (26%)
Similarity:	92/198 - (46%)	Gaps:	15/198 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 HIWPFHELCARLEANVSQGLTSEAAGRKLARNGKNVLPLPTKLELRPW-IFLKSCFSILGIIILL 109
            |.....|:.:....|.|.|||.:...|...:.|.|.||......:  | :.::....:|..|:||
Zfish     5 HTKSVEEVYSNFSVNESTGLTLDQVKRNRDKWGPNELPAEEGKSI--WELVIEQFEDLLVRILLL 67

  Fly   110 SSIASFAMYYLFATKTPDNGKVDPEFLVAGIILLVTFFLAGLTVQMQGDDDEDMLIAFDELMPMY 174
            ::..||.:.:....:......|:| |::  :::|:...:.|:   .|..:.|:.:.|..|..|..
Zfish    68 AACISFVLAWFEEGEETITAFVEP-FVI--LLILIANAIVGV---WQERNAENAIEALKEYEPEM 126

  Fly   175 CTVIRDGEKEV--IRTQDLVPGDTLPIKYGQRLPADMRF--FSTTGLELNNVALTGHSKPM--HI 233
            ..|.|...|.|  |:.:|:||||.:.:..|.::|||:|.  ..:|.|.::...|||.|..:  |.
Zfish   127 GKVYRQDRKSVQRIKAKDIVPGDIVEVAVGDKVPADIRISAIKSTTLRVDQSILTGESVSVIKHT 191

  Fly   234 TPL 236
            .|:
Zfish   192 DPV 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	19/71 (27%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	28/93 (30%)
atp2a2a	XP_005166855.1	Cation_ATPase_N	4..72	CDD:279080	17/68 (25%)
		ATPase-IIA1_Ca	53..987	CDD:273452	39/148 (26%)
		E1-E2_ATPase	93..340	CDD:278548	30/107 (28%)
		Cation_ATPase	419..526	CDD:289987
		HAD	<604..710	CDD:289480
		Cation_ATPase_C	782..985	CDD:279079
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573935
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930