DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and Atp13a2

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	XP_006239308.1	Gene:	Atp13a2 / 362645	RGDID:	1307977	Length:	1173	Species:	Rattus norvegicus

Alignment Length:	261	Identity:	57/261 - (21%)
Similarity:	102/261 - (39%)	Gaps:	66/261 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SKWRGRWCRSRRKKKEE--RESLQQTENELWLEYFSPY--LHIWPFHELCARLEANVSQGLTSEA 69
            |.|:......|:|:.::  |..:.|.:..:|:|....:  :.:......|..:..: |.||:.:.
  Rat   140 SMWQDTTQLHRQKEAKQVLRYYILQGQRYVWMETQQAFCQVSLLDHGRACDDIHCS-SSGLSLQD 203

  Fly    70 AGRKLARNGKNVLPLPTKL--------ELRPWIFLKSCFSILGIIILLSSIASFAMYYLFATKTP 126
            ...:....|.||:.:|.|.        .|.|:.    .|....|.:.|:.     .||.:|...
  Rat   204 QAVRKTIYGPNVIGIPVKSYLQLLVDEALNPYY----GFQAFSIALWLAD-----HYYWYAVCI- 258

  Fly   127 DNGKVDPEFLVAGIILLVTFF-----------LAGLTVQMQGDDDEDMLIAFDELMPMYCTVIR- 179
                    ||::.|.:.::.:           :..|:|::|                    |.|
  Rat   259 --------FLISAISICLSLYKTRKQSMTLRDMVKLSVRVQ--------------------VCRP 295

  Fly   180 DGEKEVIRTQDLVPGDTLPI-KYGQRLPADMRFFSTTGLELNNVALTGHSKPMHITPLANEGRQR 243
            .||:|.:.:.:|||||.|.: :.|..:|.|....:...: :|..:|||.|.|:..|.|. ||.|.
  Rat   296 GGEEEWVDSSELVPGDCLVLPQEGGMMPCDAALVAGECV-VNESSLTGESIPVLKTALP-EGPQP 358

  Fly   244 Y 244
            |
  Rat   359 Y 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	14/78 (18%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	23/102 (23%)
Atp13a2	XP_006239308.1	P-ATPase-V	39..1116	CDD:273738	57/261 (22%)
		P5-ATPase	39..>110	CDD:289194
		E1-E2_ATPase	258..493	CDD:278548	32/133 (24%)
		Cation_ATPase	<621..658	CDD:289987
		COG4087	<843..>892	CDD:226572
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334728
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930