DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and CG6230

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_609490.1	Gene:	CG6230 / 34546	FlyBaseID:	FBgn0027582	Length:	1225	Species:	Drosophila melanogaster

Alignment Length:	273	Identity:	59/273 - (21%)
Similarity:	95/273 - (34%)	Gaps:	108/273 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 YLHI-------WPFHEL----CARLE---ANVSQGLTSEAAGRKLAR------NGKN-VLPL-PT 86
            :|||       |..|.|    |.|::   |||            ||:      ||.: ::|: .:
  Fly   116 FLHILTLLFCYWSVHVLAFLTCRRVKLPGANV------------LAKVVPTPNNGNSKIVPIRSS 168

  Fly    87 KLE----LRPWIFLKSC--------------FSILGIIILLSSIASFAMY--YLFATKTPDNGKV 131
            |||    ...::|.|:.              |.:.|::...||.......  ...||:|..|.::
  Fly   169 KLEDGSTQYYFVFQKTKYVWNEDRKTFRAVEFPVNGLLSTYSSSRGLETEEDIKRATQTYGNNEM 233

  Fly   132 D---PEF------LVAGIILLVTFFLAGLTVQMQGDDDE--------DMLIAFDELMPMYCTVIR 179
            :   |||      .......:...|..||...    ||.        .|||||:      ||:::
  Fly   234 EMVVPEFHELFIERATAPFFVFQVFSVGLWCM----DDYWYYSLFTLFMLIAFE------CTIVK 288

  Fly   180 D-----------GEKEV------------IRTQDLVPGDTLPIKYGQR---LPADMRFFSTTGLE 218
            .           |.|..            :.:.:|:|||.:.|...|.   :|.|:.....:.:
  Fly   289 QQLRNMSEIRKMGNKPYLIYAFRQNKWRHLGSDELLPGDLVSITRSQNDNIVPCDLVILRGSCI- 352

  Fly   219 LNNVALTGHSKPM 231
            ::...|||.|.|:
  Fly   353 VDESMLTGESVPL 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	24/110 (22%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	26/123 (21%)
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	59/273 (22%)
		E1-E2_ATPase	310..515	CDD:278548	13/57 (23%)
		Cation_ATPase	<590..664	CDD:289987
		COG4087	<850..901	CDD:226572
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438586
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930