DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and ATP7

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001259466.1	Gene:	ATP7 / 32142	FlyBaseID:	FBgn0030343	Length:	1254	Species:	Drosophila melanogaster

Alignment Length:	193	Identity:	48/193 - (24%)
Similarity:	73/193 - (37%)	Gaps:	48/193 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LCARLEANVSQGLTSEA---AGR-KLARNGKNVLPLPTKLELRPW--IFLKSCFSILGIIILLSS 111
            :|..:||     |..||   .|| |:|.|     .|..|.|:|.|  .||.|        ::...
  Fly   338 ICEAIEA-----LGFEAKLMTGRDKMAHN-----YLEHKEEIRKWRNAFLVS--------LIFGG 384

  Fly   112 IASFAMYYLFATKTPDNGKVDPEFLVAGIIL--LVTF-------FLAGLTVQMQ-------GDDD 160
            ....||.| |..:..|.|..:...||.|:.:  ||.|       |..|....:|       |..:
  Fly   385 PCMVAMIY-FMLEMSDKGHANMCCLVPGLSMENLVMFLLSTPVQFFGGFHFYVQSYRAIKHGTTN 448

  Fly   161 EDMLIAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIKYGQRLPADMRFFSTTGLELNNVA 223
            .|:||:      |..|:.......|:....|:..::.|:.:.. .|..:..|.:.|..|.::|
  Fly   449 MDVLIS------MVTTISYVYSVAVVIAAVLLEQNSSPLTFFD-TPPMLLIFISLGRWLEHIA 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	19/69 (28%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	20/100 (20%)
ATP7	NP_001259466.1	HMA	16..78	CDD:238219
		HMA	97..159	CDD:238219
		HMA	214..274	CDD:238219
		ZntA	285..1131	CDD:225127	48/193 (25%)
		HMA	287..350	CDD:238219	5/16 (31%)
		E1-E2_ATPase	489..735	CDD:278548	4/16 (25%)
		COG4087	<984..1085	CDD:226572
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438582
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930