DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and Atp2b3

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	XP_038955468.1	Gene:	Atp2b3 / 29599	RGDID:	621304	Length:	1330	Species:	Rattus norvegicus

Alignment Length:	220	Identity:	51/220 - (23%)
Similarity:	87/220 - (39%)	Gaps:	54/220 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LCARLEANVSQGLTSEAAGRKLARN--GKNVLPLPTKLELRPWIFLKSCFSILG----IIILLSS 111
            ||.||:.:.::||.......:..|.  |:|.:|     ..:|..||:..:..|.    ||:.:::
  Rat    59 LCRRLKTSPTEGLADNTNDLEKRRQIYGQNFIP-----PKQPKTFLQLVWEALQDVTLIILEVAA 118

  Fly   112 IASFAMYYL------------FATKTPDNGKVDPEFLVAGIIL-------LVTFF--------LA 149
            |.|..:.:.            .:....|.|:.:..::....||       |||.|        ..
  Rat   119 IVSLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 183

  Fly   150 GLTVQMQGDDDEDMLIAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIKYGQRLPADMRFFST 214
            ||..:::.:..              .||||:|:...:....||.||...:|||..||||......
  Rat   184 GLQSRIEQEQK--------------FTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQG 234

  Fly   215 TGLELNNVALTGHSKPMHITPLANE 239
            ..|:::..:|||.|.  |:...|::
  Rat   235 NDLKIDESSLTGESD--HVRKSADK 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	18/69 (26%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	29/104 (28%)
Atp2b3	XP_038955468.1	ATPase-IIB_Ca	19..1142	CDD:273668	51/220 (23%)
Atp2b3	XP_038955468.1	ATP_Ca_trans_C	1181..1256	CDD:403580
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334706
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930