Protein Alignment CG45063 and Atp1a2

DIOPT Version :10

• Sequence 1: NP_001286728.1
• Gene: CG45063 / 19835490
• FlyBaseID: FBgn0266433
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_036637.1
• Gene: Atp1a2 / 24212
• RGDID: 2168
• Length: 1020
• Species: Rattus norvegicus
• Alignment Length: 219
• Identity: 66/219 - (30%)
• Similarity: 113/219 - (51%)
• Gaps: 17/219 - (7%)

  Fly    21 KKKEERESLQQTENELWLEYFSPYLHIWPFHELCARLEANVSQGLTSEAAGRKLARNGKNVL-PL 84
            |||::.:.|.:.:.|:.::.     |.....||..:.:.::|:|||::.|...|||:|.|.| |.
  Rat    22 KKKQKEKELDELKKEVAMDD-----HKLSLDELGRKYQVDLSKGLTNQRAQDILARDGPNALTPP 81

  Fly    85 PTKLELRPWI-FLKSCFSILGIIILLSSIASFAMYYLFAT--KTPDNGKVDPEFLVAGIILLVTF 146
            ||..|   |: |.:..|....|::.:.::..|..|.:.|.  ..|.|     :.|..||:|....
  Rat    82 PTTPE---WVKFCRQLFGGFSILLWIGALLCFLAYGILAAMEDEPSN-----DNLYLGIVLAAVV 138

  Fly   147 FLAGLTVQMQGDDDEDMLIAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIKYGQRLPADMRF 211
            .:.|.....|......::.:|..::|....|||:|||..|..:::|.||.:.:|.|.|:|||:|.
  Rat   139 IVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRI 203

  Fly   212 FSTTGLELNNVALTGHSKPMHITP 235
            .|:.|.:::|.:|||.|:|...:|
  Rat   204 ISSHGCKVDNSSLTGESEPQTRSP 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	ATPase-IIC_X-K	21..>230	CDD:273445	64/212 (30%)
Atp1a2	NP_036637.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		3/8 (38%)
		ATPase-IIC_X-K	30..1020	CDD:273445	63/211 (30%)
		Interaction with phosphoinositide-3 kinase. /evidence=ECO:0000250	80..82		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..231		7/16 (44%)