DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and Atp2c1

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001240760.1	Gene:	Atp2c1 / 235574	MGIID:	1889008	Length:	952	Species:	Mus musculus

Alignment Length:	241	Identity:	62/241 - (25%)
Similarity:	101/241 - (41%)	Gaps:	26/241 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 RRKKKEER----ESLQQTENELWLEYF-SPYLHIWPFHELCARLEANVSQGLTSEAAGRKLARNG 78
            |.::.||:    :.:...|||..:... |.........|:...|:|::..||.......:.|.:|
Mouse    29 RSQRAEEQVARFQKIPNVENETMIPVLTSKRASELAVSEVAGLLQADLQNGLNKSEVSHRRAFHG 93

  Fly    79 KNVLPLPTKLELRPWIFLKSCFSILGIIILLSSIASFAMYYLFATKTPDNGKVDPEFLVAGIILL 143
            .|...:.....|  |....|.|....|::||:|.....:...|.         |...:...|:::
Mouse    94 WNEFDISEDEPL--WKKYISQFKNPLIMLLLASAVISILMRQFD---------DAVSITVAIVIV 147

  Fly   144 VTFFLAGLTVQMQGDDDEDMLIAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIKYGQRLPAD 208
            ||      ...:|....|..|....:|:|..|..:|:|:.|....:|||||||:.:..|.|:|||
Mouse   148 VT------VAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPAD 206

  Fly   209 MRFFSTTGLELNNVALTGHSKP-MHIT---PLANEGRQRYSRIEYI 250
            :|.|....|.::..:|||.:.| ..:|   |.||......|.|.::
Mouse   207 LRLFEAVDLSVDESSLTGETAPCSKVTAPQPAANGDLASRSNIAFM 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	16/70 (23%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	30/89 (34%)
Atp2c1	NP_001240760.1	ATPase-IIA2_Ca	57..936	CDD:130585	56/213 (26%)
		Cation_ATPase_N	60..128	CDD:279080	16/69 (23%)
		E1-E2_ATPase	152..372	CDD:278548	34/101 (34%)
		Cation_ATPase	443..526	CDD:289987
		COG4087	589..712	CDD:226572
		Cation_ATPase_C	759..931	CDD:279079
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831001
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840