DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and eat-6

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_506269.1	Gene:	eat-6 / 179796	WormBaseID:	WBGene00001137	Length:	996	Species:	Caenorhabditis elegans

Alignment Length:	220	Identity:	71/220 - (32%)
Similarity:	117/220 - (53%)	Gaps:	21/220 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 KKEERESLQQTENELWLEYFSPYLHIWPFHELCARLEANVSQGLTSEAAGRKLARNGKNVLPLPT 86
            ||::::.|...:.|:.::.     ||.|..||.|||..|:..|||.:.|...||:||.|.|..|
Worm     3 KKDKKQELHDLKQEVKMDE-----HIVPIEELVARLGTNLETGLTRQKAQEVLAKNGPNALSPP- 61

  Fly    87 KLELRP-WI-FLKSCFSILGIIILLSSIASFAMYYL--FATKTP--DNGKVDPEFLVAGIILLVT 145
              |..| || |.|:.|....:::.:.:|..:..|.:  |..:.|  ||       |..||:|:..
Worm    62 --ETTPEWIKFCKNLFGGFAMLLWVGAILCYIAYSVDYFTMEYPSKDN-------LYLGIVLMTV 117

  Fly   146 FFLAGLTVQMQGDDDEDMLIAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIKYGQRLPADMR 210
            ..:.|:....|......::.:|..::|.:..|.|||:|:.::|::||.||.:.:|.|.|:|||:|
Worm   118 VVITGVFQYYQESKSSKIMDSFKNMVPTFALVHRDGQKQQVKTEELVVGDIVEVKGGDRVPADLR 182

  Fly   211 FFSTTGLELNNVALTGHSKPMHITP 235
            ..|..|.:::|.:|||.|:|...:|
Worm   183 VVSAFGFKVDNSSLTGESEPQSRSP 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	28/72 (39%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	30/89 (34%)
eat-6	NP_506269.1	ATPase-IIC_X-K	6..996	CDD:273445	69/217 (32%)
		Cation_ATPase_N	18..92	CDD:214842	28/81 (35%)
		E1-E2_ATPase	112..343	CDD:278548	32/96 (33%)
		Cation_ATPase	404..494	CDD:289987
		COG4087	<644..725	CDD:226572
		Cation_ATPase_C	772..981	CDD:279079
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156293
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S851
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.790