DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and mca-2

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_500161.1	Gene:	mca-2 / 177004	WormBaseID:	WBGene00019875	Length:	1158	Species:	Caenorhabditis elegans

Alignment Length:	213	Identity:	58/213 - (27%)
Similarity:	89/213 - (41%)	Gaps:	27/213 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LCARLEANVSQGL---TSEAAGRKLARNGKNVLPLPTKLELR-PWIFLKSCFSILGIIILLSSIA 113
            ||.:|:.:...||   |.|...|:.|.....:.|.|:|...| .|..|:   .|..:|:|::::.
Worm    39 LCRKLKTDPINGLPNDTKELEHRRTAFGKNEIPPAPSKSFFRLAWEALQ---DITLVILLVAALV 100

  Fly   114 SFAM-YYLFATKTPDNGKVDPEF-LVAGIILLVTFFLAGLTVQMQGDDDEDMLIAFDELMPMYCT 176
            |..: :|....:...|...:.|. .:.|:.:||...:..|...:.....|..   |..|.....|
Worm   101 SLGLSFYKPPAEHASNDSSESEAGWIEGVAILVAVLVVVLVTALNDWTKEKQ---FRGLQSKIET 162

  Fly   177 -----VIRDGEKEVIRTQDLVPGDTLPIKYGQRLPADMRFFSTTGLELNNVALTGHS----KPMH 232
                 |||.||...|...:||.||...:|||..||||.....:..|:::..:|||.|    |...
Worm   163 EHKFSVIRGGEPLDIVVNELVVGDIARVKYGDLLPADGLLIQSNDLKIDESSLTGESDLIRKSEE 227

  Fly   233 ITPL------ANEGRQRY 244
            ..|:      |.||..|:
Worm   228 FDPVLLSGTHAMEGSGRF 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	19/67 (28%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	29/98 (30%)
mca-2	NP_500161.1	ATPase-IIB_Ca	5..1026	CDD:273668	58/213 (27%)
		Cation_ATPase_N	35..101	CDD:279080	18/64 (28%)
		E1-E2_ATPase	168..413	CDD:278548	28/78 (36%)
		Cation_ATPase	475..564	CDD:289987
		HAD	<648..767	CDD:289480
		Cation_ATPase_C	841..1020	CDD:279079
		ATP_Ca_trans_C	1073..>1096	CDD:289209
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156291
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930