DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and cua-1

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001255202.1	Gene:	cua-1 / 176770	WormBaseID:	WBGene00000834	Length:	1238	Species:	Caenorhabditis elegans

Alignment Length:	188	Identity:	34/188 - (18%)
Similarity:	63/188 - (33%)	Gaps:	62/188 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RESLQQTENELWLEYFSPY--------LHIWPFHELCARLEANVSQGLTSEAAGRKLARNGKNVL 82
            |..:||..::: ..||.|:        |.:|.:.|..:...||:..||..|.|
Worm   675 RAPIQQLADKI-AGYFVPFVIVLSLFTLGVWIYIEYNSARNANLPPGLRFEEA------------ 726

  Fly    83 PLPTKLELRPWIFLKSCFSILGIIILLSSIASFAMYYLFATKTPDNGKVDPEFLVAGIILLVTFF 147
                         ||..|.....::.::...|..:    ||.|              .:::.|..
Worm   727 -------------LKIAFEAAITVLAIACPCSLGL----ATPT--------------AVMVGTGV 760

  Fly   148 LAGLTVQMQGDDDEDML-----IAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIK 200
            .|...:.::|.:..:.:     |.||:     ...|.:|...|::....|...|:.:|
Worm   761 GAANGILIKGGEPLESVHKVTTIVFDK-----TGTITEGRPRVVQIASFVNPSTMSLK 813

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	12/70 (17%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	12/66 (18%)
cua-1	NP_001255202.1	HMA	50..113	CDD:238219
		HMA	134..196	CDD:238219
		HMA	253..317	CDD:238219
		ZntA	330..1117	CDD:225127	34/188 (18%)
		HMA	332..389	CDD:278815
		E1-E2_ATPase	534..775	CDD:278548	25/143 (17%)
		COG4087	961..1082	CDD:226572
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156283
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930