DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45063 and Atp4a

DIOPT Version :9

Sequence 1:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001277556.1	Gene:	Atp4a / 11944	MGIID:	88113	Length:	1034	Species:	Mus musculus

Alignment Length:	223	Identity:	62/223 - (27%)
Similarity:	103/223 - (46%)	Gaps:	19/223 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 KKKEERESLQQTENELWLEYFSPYLHIWPFHELCARLEANVSQGLTSEAAGRKLARNGKNVLPLP 85
            ||||:.|:::: |.|:       ..|.....||..:.:.:.::||.:..|...|.|:|.|.|..|
Mouse    37 KKKEKLENMKK-EMEI-------NDHQLSVSELEQKYQTSATKGLKASLAAELLLRDGPNALRPP 93

  Fly    86 TKLELRPWIFLKSCFSILGIIILLSSIASFAMYYLFATKTPDNGKVDPEFLVAGIILLVTFFLAG 150
            ....    .::|....:.|.:..|..:|:......||.:..:......:.|...:.|:....:.|
Mouse    94 RGTP----EYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLAVALIAVVVVTG 154

  Fly   151 LTVQMQGDDDEDMLIAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIKYGQRLPADMRFFSTT 215
            .....|.....:::.:|..|:|...||||||:|..|....||.||.:.:|.|.|:|||:|..|..
Mouse   155 CFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILSAQ 219

  Fly   216 GLELNNVALTGHSKPM-------HITPL 236
            |.:::|.:|||.|:|.       |.:||
Mouse   220 GCKVDNSSLTGESEPQTRSPECTHESPL 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	16/70 (23%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	32/89 (36%)
Atp4a	NP_001277556.1	H-K_ATPase_N	2..>27	CDD:286172
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	14..40		2/2 (100%)
		ATPase-IIC_X-K	42..1034	CDD:273445	58/218 (27%)
		Cation_ATPase_N	50..124	CDD:214842	17/84 (20%)
		E1-E2_ATPase	156..375	CDD:278548	34/92 (37%)
		Cation_ATPase	437..531	CDD:289987
		COG4087	616..>742	CDD:226572
		Cation_ATPase_C	809..1018	CDD:279079
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831019
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840