Protein Alignment PIG-V and PIGV

DIOPT Version :10

• Sequence 1: NP_001286508.1
• Gene: PIG-V / 19835383
• FlyBaseID: FBgn0265174
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_060307.2
• Gene: PIGV / 55650
• HGNCID: 26031
• Length: 493
• Species: Homo sapiens
• Alignment Length: 504
• Identity: 156/504 - (30%)
• Similarity: 255/504 - (50%)
• Gaps: 76/504 - (15%)

  Fly     3 EKVTKLALASRLIVLLVQLVANGALPEHKPDVFRMPVSSDQNASWIDKVIKRCLGGLRHWDGEYF 67
            ::|.:.|::.|::.|::|.:.|..:|:|..:.|..|..:.  :.::|::::..||||.|||.|:|
Human     9 KEVLRFAVSCRILTLMLQALFNAIIPDHHAEAFSPPRLAP--SGFVDQLVEGLLGGLSHWDAEHF 71

  Fly    68 LHIAENLYSYENTLAFYPLYPVVVRHVGQAVEAIGISLSQESILLVVAVALNFWLFCESANLLFQ 132
            |.|||:.|.||:..||:|.:|:.:....:.:..:...||..|.||:...:|||..|..:|..|..
Human    72 LFIAEHGYLYEHNFAFFPGFPLALLVGTELLRPLRGLLSLRSCLLISVASLNFLFFMLAAVALHD 136

  Fly   133 LTQVLFNDLNKSWNAALIYCFNPATIFFTAAYSETFFAYSSLHLM--LECSKPTGSFRYLRLGTA 195
            |..::.:..::|:.|||::|.:||.:|..|.|||..||..:...|  ||..:...|.......|.
Human   137 LGCLVLHCPHQSFYAALLFCLSPANVFLAAGYSEALFALLTFSAMGQLERGRVWTSVLLFAFATG 201

  Fly   196 LAACLLCRSNGLITLGYPLY-----FFGRQLLLKNKEPNTCMQLTQMTLTILGAIGIL----HTY 251
            :      |||||:::|:.::     ||....:|     |...||.::..::..::..|    ..:
Human   202 V------RSNGLVSVGFLMHSQCQGFFSSLTML-----NPLRQLFKLMASLFLSVFTLGLPFALF 255

  Fly   252 YFYIYRLYCLPNTRPNHPQHIVDYAVERKYLLSGQGSEGSPWCQYTLPFPYTYVQSHYWDVGFLR 316
            .:|.|..:|||.:....|:.:|..||::.|.:: :|:| .|||.:.:|..|:|:|..||:||||:
Human   256 QYYAYTQFCLPGSARPIPEPLVQLAVDKGYRIA-EGNE-PPWCFWDVPLIYSYIQDVYWNVGFLK 318

  Fly   317 YYKWKQLPNFLLALPMLSFMHWHCYDYMQHLAKAVWAKLTPSGFKELIRDHT------------T 369
            ||:.||:||||||.|:...:.|..:.|   :....|..|| .|.:....:.|            .
Human   319 YYELKQVPNFLLAAPVAILVAWATWTY---VTTHPWLCLT-LGLQRSKNNKTLEKPDLGFLSPQV 379

  Fly   370 FPFVLHAAILTLVCTVYVHIQVSTRLLASATPVFYWFAA----DHMP-----KTLAQLKLRSKA- 424
            |.:|:|||:|.|...:.:|:||.||.|.|:||:.|||.|    |..|     ||:....|...:
Human   380 FVYVVHAAVLLLFGGLCMHVQVLTRFLGSSTPIMYWFPAHLLQDQEPLLRSLKTVPWKPLAEDSP 444

  Fly   425 -----------GALFVWCT-------------TYSLVGTVLFSNNYPWT 449
                       |.|:.|.|             ||.|:|.:|..|..|||
Human   445 PGQKVPRNPIMGLLYHWKTCSPVTRYILGYFLTYWLLGLLLHCNFLPWT 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-V	NP_001286508.1	PMT_2	5..449	CDD:473917	154/500 (31%)
PIGV	NP_060307.2	Mannosyl_trans2	8..493	CDD:282094	154/502 (31%)