Protein Alignment CG45062 and mgtA

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_418663.1
• Gene: mgtA / 948778
• ECOCYCID: EG12525
• Length: 898
• Species: Escherichia coli
• Alignment Length: 686
• Identity: 152/686 - (22%)
• Similarity: 275/686 - (40%)
• Gaps: 164/686 - (23%)

  Fly    19 THAISGIGFAVALACGRNTEVGSMTDLCFKERSRSRS-QKHQKQISYYMLLVAIVCFILLFLTTG 82
            |..:||...|:.:|.|.||..|.:.....::.|...: |:...::|..::...:|...::.|..|
E. coli   244 TTVVSGTAQAMVIATGANTWFGQLAGRVSEQESEPNAFQQGISRVSMLLIRFMLVMAPVVLLING 308

  Fly    83 FEHGHIVYEV---NLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRNLRATCTLGLSTVIVS 144
            :..|. .:|.   .||:.:||||..||.|:...|.|...::.:::..|::|.|....|...::.:
E. coli   309 YTKGD-WWEAALFALSVAVGLTPEMLPMIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCT 372

  Fly   145 DLVGTMTKRRMRVSEIFVDMGLLSVDNLDVSAQSPRFIELIRASVLCNDAVICPGNIGVPKMQKD 209
            |..||:|:.:           ::..::.|:|.::.   |.:..|...|...    ..|:.
E. coli   373 DKTGTLTQDK-----------IVLENHTDISGKTS---ERVLHSAWLNSHY----QTGLK----- 414

  Fly   210 MYGNILDIALLKFGLMILPSIDLLRHDHEKVAN--KHYNSEDKVQVTVHRTR-------DADGHL 265
               |:||.|:|:            ..|.|...:  ..:...|::.....|.|       :.:.|
E. coli   415 ---NLLDTAVLE------------GTDEESARSLASRWQKIDEIPFDFERRRMSVVVAENTEHH- 463

  Fly   266 KLVLLMKGHCEVVIRRCSTFAIRDEELPLDEQLQEIILSLADGLLEAGRHVRAFAYKELSDELEF 330
              .|:.||..:.::..||......|.:|||:.:...|..:.|.|...|..|.|.|.|.|
E. coli   464 --QLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNRQGLRVVAVATKYL------ 520

  Fly   331 RRFSQVNTGLEGGEYKYRDYLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRK 395
                   ...||      ||...|...|...|.||..:||:.|...|:...:|:||.:.::|...
E. coli   521 -------PAREG------DYQRADESDLILEGYIAFLDPPKETTAPALKALKASGITVKILTGDS 572

  Fly   396 PKMAKALAVDVGILPAPSDTFQAV---NLKRMPPTAEVVDMSQ----YADEKPQHQRRHIEQLIL 453
            ..:|..:..:||:     |..:.|   :::.:... |:.:::|    :|...|.|:.|
E. coli   573 ELVAAKVCHEVGL-----DAGEVVIGSDIETLSDD-ELANLAQRTTLFARLTPMHKER------- 624

  Fly   454 NQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGVAKYGSAVMCEASADLI 518
                             |....:|.|.||..:|..::|.||:|::.:|::..|:..:...:||:|
E. coli   625 -----------------IVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADII 672

  Fly   519 LLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICN---ILVYLFF--FLLGIPLYIHIMDELI 578
            ||:.|...|...|.:.|..|.|:.|.:....::|..|   :||...|  ||..:||::.|.:
E. coli   673 LLEKSLMVLEEGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQN--- 734

  Fly   579 LAFLVNLVPALTLIYEP-----PEENL---MLQMPKVYD------------------DFLLNSRL 617
                        |:|:.     |.:|:   .:|.|:.::                  |.|....:
E. coli   735 ------------LLYDVSQVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLM 787

  Fly   618 FFVSHILVGTIEAAAVFMT-YFVFMADKGFLPRTLV 652
            ::|.|  ..|.|...:|.: :||.    |.|.:||:
E. coli   788 WWVFH--ANTPETQTLFQSGWFVV----GLLSQTLI 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	152/686 (22%)
mgtA	NP_418663.1	PRK10517	1..898	CDD:236705	152/686 (22%)