Protein Alignment CG45062 and PMA2

DIOPT Version :9

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_015289.1
• Gene: PMA2 / 856071
• SGDID: S000005957
• Length: 947
• Species: Saccharomyces cerevisiae
• Alignment Length: 758
• Identity: 155/758 - (20%)
• Similarity: 292/758 - (38%)
• Gaps: 191/758 - (25%)

  Fly    23 SGIGFAVALACGRNTEVGSMTDLCFKERSRSRSQKHQKQISY---YMLLVAIVCFILLFLTTGFE 84
            :|..|.|..|.|.||.||....|.   ...|..:.|..::..   .:|||.::..:||..|..|.
Yeast   282 TGEAFMVVTATGDNTFVGRAAALV---GQASGVEGHFTEVLNGIGIILLVLVIATLLLVWTACFY 343

  Fly    85 HGHIVYEVNLSLLIGLT----PVYLPFILYWGLRRTRKEMGRKQCHVRNLRATCTLGLSTVIVSD 145
            ....:..: |...:|:|    ||.||.::...:......:.:||..|:.|.|..:|....::.||
Yeast   344 RTVGIVSI-LRYTLGITIIGVPVGLPAVVTTTMAVGAAYLAKKQAIVQKLSAIESLAGVEILCSD 407

  Fly   146 LVGTMTKRRMRVSEIFVDMGLLSVDNLDVSA-----QSPRFIELIRASVLCNDAVICPGNIGVPK 205
            ..||:||.::.:.|.:...| :|.|:|.::|     :..:.::.|       |.......|..||
Yeast   408 KTGTLTKNKLSLHEPYTVEG-VSPDDLMLTACLAASRKKKGLDAI-------DKAFLKSLIEYPK 464

  Fly   206 MQKDMYGNILDIALLKFGLMILPSIDLLRHDHEKVANKHYNSEDKVQVTVHRTRDADGHLKLVLL 270
             .||        ||.|:.::..       |..:.|:.|         ||.           :|..
Yeast   465 -AKD--------ALTKYKVLEF-------HPFDPVSKK---------VTA-----------VVES 493

  Fly   271 MKGHCEVVIRRCSTFAIR--DEELPLDEQLQEIILSLADGLLEAGRHVRAFAYKELSDELEFRRF 333
            .:|...|.::....|.::  :|:.|:.|.:.|                   .|:....||..|.|
Yeast   494 PEGERIVCVKGAPLFVLKTVEEDHPIPEDVHE-------------------NYENKVAELASRGF 539

  Fly   334 SQVNTGLEGGEYKYRDYLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKM 398
            ..:....:.||..:           ..||::...:|||....:.::..|..|:::.::|.....:
Yeast   540 RALGVARKRGEGHW-----------EILGVMPCMDPPRDDTAQTINEARNLGLRIKMLTGDAVGI 593

  Fly   399 AKALAVDVGILPAPSDTFQAVNLKRM-------PPTAEVVDMSQ----YADEKPQHQRRHIEQLI 452
            ||.....:|:      .....|.:|:       .|.:|:.|..:    :|:..|||:.|.:|.|
Yeast   594 AKETCRQLGL------GTNIYNAERLGLGGGGDMPGSELADFVENADGFAEVFPQHKYRVVEIL- 651

  Fly   453 LNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGVAKYGSAVMCEASADL 517
                                   :..|.:|::.|..::|.|:::.:..|:|..|:.....::||:
Yeast   652 -----------------------QNRGYLVAMTGDGVNDAPSLKKADTGIAVEGATDAARSAADI 693

  Fly   518 ILLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICNILVYLFFFL-LGIPLYIHIMDELILAF 581
            :.|....:.::..:..||.:|..:...:.|.:|.::     :|..|| |.|.:..:.:|..::.|
Yeast   694 VFLAPGLSAIIDALKTSRQIFHRMYSYVVYRIALSL-----HLEIFLGLWIAILNNSLDINLIVF 753

  Fly   582 LVNL--VPALTLIY-------EPPEENLMLQMPKVYDDFLLNSRLFFVSHILVGTIEAAAVFMTY 637
            :...  |..||:.|       ||.:.||              .||:.:| |::|.:.|...::|.
Yeast   754 IAIFADVATLTIAYDNAPYAPEPVKWNL--------------PRLWGMS-IILGIVLAIGSWITL 803

  Fly   638 FVFMADKGFLPRTLVALN------IAWHDDMLDDITDSFGQEWSSEARRQLECQVSSLCLMSLAV 696
            .......|.:.:...|:|      |:..::.|..:|.:.|..|||....||...|.::.:  :|.
Yeast   804 TTMFLPNGGIIQNFGAMNGVMFLQISLTENWLIFVTRAAGPFWSSIPSWQLAGAVFAVDI--IAT 866

  Fly   697 M---------QCTNLVLTKTGRANLLAHGFRNWLLSLAVLLLI 730
            |         ..|::|..           .|.|:.|:.:..::
Yeast   867 MFTLFGWWSENWTDIVSV-----------VRVWIWSIGIFCVL 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	E1-E2_ATPase	<13..132	CDD:278548	30/115 (26%)
		Cation_ATPase	190..284	CDD:289987	17/93 (18%)
		Cation_ATPase_C	582..777	CDD:295563	35/173 (20%)
PMA2	NP_015289.1	P-type_ATPase_H	116..903	CDD:319771	155/758 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341383
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930