Protein Alignment CG45062 and PMA1

DIOPT Version :9

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_011507.1
• Gene: PMA1 / 852876
• SGDID: S000002976
• Length: 918
• Species: Saccharomyces cerevisiae
• Alignment Length: 767
• Identity: 160/767 - (20%)
• Similarity: 291/767 - (37%)
• Gaps: 211/767 - (27%)

  Fly    24 GIGFAVALACGRNTEVGSMTDLCFKERSRSRSQKHQKQISY---YMLLVAIVCFILLFLTTGFEH 85
            |.||.|..|.|.||.||....|..|   .:..|.|..::..   .:|||.::..:||..|..|
Yeast   254 GEGFMVVTATGDNTFVGRAAALVNK---AAGGQGHFTEVLNGIGIILLVLVIATLLLVWTACF-- 313

  Fly    86 GHIVYEVN-----LSLLIGLT----PVYLPFILYWGLRRTRKEMGRKQCHVRNLRATCTLGLSTV 141
                |..|     |...:|:|    ||.||.::...:......:.:||..|:.|.|..:|....:
Yeast   314 ----YRTNGIVRILRYTLGITIIGVPVGLPAVVTTTMAVGAAYLAKKQAIVQKLSAIESLAGVEI 374

  Fly   142 IVSDLVGTMTKRRMRVSEIFVDMGLLSVDNLDVSAQSPRFIELIRASVLCNDAVICPGNIGVPKM 206
            :.||..||:||.::.:.|.:...| :|.|:|.::|                    |   :...:.
Yeast   375 LCSDKTGTLTKNKLSLHEPYTVEG-VSPDDLMLTA--------------------C---LAASRK 415

  Fly   207 QKDMYGNILDIALLKFGLMILPSIDLLR-------HDHEKVANKHYNSEDKVQVTVHRTRDADGH 264
            :|.:  :.:|.|.||.......:.|.|.       |..:.|:.|         ||.
Yeast   416 KKGL--DAIDKAFLKSLKQYPKAKDALTKYKVLEFHPFDPVSKK---------VTA--------- 460

  Fly   265 LKLVLLMKGHCEVVIRRCSTFAIR--DEELPLDEQLQEIILSLADGLLEAGRHVRAFAYKELSDE 327
              :|...:|...|.::....|.::  :|:.|:.|.:.|                   .|:....|
Yeast   461 --VVESPEGERIVCVKGAPLFVLKTVEEDHPIPEDVHE-------------------NYENKVAE 504

  Fly   328 LEFRRFSQVNTGLEGGEYKYRDYLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVT 392
            |..|.|..:....:.||..:           ..||::...:|||....:.|...|..|:::.::|
Yeast   505 LASRGFRALGVARKRGEGHW-----------EILGVMPCMDPPRDDTAQTVSEARHLGLRVKMLT 558

  Fly   393 QRKPKMAKALAVDVGILPAPSDTFQAVNLKRM-------PPTAEVVDMSQ----YADEKPQHQRR 446
            .....:||.....:|:      .....|.:|:       .|.:|:.|..:    :|:..|||:.|
Yeast   559 GDAVGIAKETCRQLGL------GTNIYNAERLGLGGGGDMPGSELADFVENADGFAEVFPQHKYR 617

  Fly   447 HIEQLILNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGVAKYGSAVMC 511
            .:|.|                        :..|.:|::.|..::|.|:::.:..|:|..|:....
Yeast   618 VVEIL------------------------QNRGYLVAMTGDGVNDAPSLKKADTGIAVEGATDAA 658

  Fly   512 EASADLILLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICNILVYLFFFLLGIPLYIHIMD- 575
            .::||::.|....:.::..:..||.:|..:...:.|.:|.::     :|..||   .|:|.|:|
Yeast   659 RSAADIVFLAPGLSAIIDALKTSRQIFHRMYSYVVYRIALSL-----HLEIFL---GLWIAILDN 715

  Fly   576 ----ELILAFLVNL-VPALTLIYE-------PPEENLMLQMPKVYDDFLLNSRLFFVSHILVGTI 628
                :||:...:.. |..|.:.|:       |.:.||              .||:.:| |::|.:
Yeast   716 SLDIDLIVFIAIFADVATLAIAYDNAPYSPKPVKWNL--------------PRLWGMS-IILGIV 765

  Fly   629 EAAAVFMTYFVFMADKGFLPRTLVALN------IAWHDDMLDDITDSFGQEWSSEARRQLECQVS 687
            .|...::|.......||.:.:...|:|      |:..::.|..||.:.|..|||....||...|.
Yeast   766 LAIGSWITLTTMFLPKGGIIQNFGAMNGIMFLQISLTENWLIFITRAAGPFWSSIPSWQLAGAVF 830

  Fly   688 SLCLMSLAVM---------QCTNLVLTKTGRANLLAHGFRNWLLSLAVLLLI 730
            ::.:  :|.|         ..|::|..           .|.|:.|:.:..::
Yeast   831 AVDI--IATMFTLFGWWSENWTDIVTV-----------VRVWIWSIGIFCVL 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	E1-E2_ATPase	<13..132	CDD:278548	34/119 (29%)
		Cation_ATPase	190..284	CDD:289987	16/100 (16%)
		Cation_ATPase_C	582..777	CDD:295563	35/172 (20%)
PMA1	NP_011507.1	P-type_ATPase_H	87..874	CDD:319771	160/767 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341382
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930