Protein Alignment CG45062 and CCC2

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_010556.1
• Gene: CCC2 / 851862
• SGDID: S000002678
• Length: 1004
• Species: Saccharomyces cerevisiae
• Alignment Length: 649
• Identity: 115/649 - (17%)
• Similarity: 200/649 - (30%)
• Gaps: 269/649 - (41%)

  Fly    35 RNTEVGSMTDLCFKERSRSRSQKHQKQISYY-----------MLLVAIV-----CFIL------- 76
            |.|.||..|.|....:....:|..:..|..|           :|::|::     ||||
Yeast   492 RTTTVGEETKLANIIKVMKEAQLSKAPIQGYADYLASIFVPGILILAVLTFFIWCFILNISANPP 556

  Fly    77 --LFLTTGFEHGHIVYEVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRNLRATCTLGLS 139
              ....|..::..|..:...|::|...|                               |.|||:
Yeast   557 VAFTANTKADNFFICLQTATSVVIVACP-------------------------------CALGLA 590

  Fly   140 T---VIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNLDVSAQSPRFIELIRASVLCNDAVICPGNI 201
            |   ::|...||......::..|:......::....|                  ....:..|.:
Yeast   591 TPTAIMVGTGVGAQNGVLIKGGEVLEKFNSITTFVFD------------------KTGTLTTGFM 637

  Fly   202 GVPKMQKD--MYGNILDIALLKFGLMILPSIDLLRHDHEKVANKHYNSEDKVQVTVHRTRDADGH 264
            .|.|..||  ..||:                                .||:|...:..|.....|
Yeast   638 VVKKFLKDSNWVGNV--------------------------------DEDEVLACIKATESISDH 670

  Fly   265 ------------------LKLVLLM------KGHCEVVIRRCST------FAIRDEELPLDEQLQ 299
                              |..|:|.      ||    ::.:|..      ..|.:|.|.|::.|:
Yeast   671 PVSKAIIRYCDGLNCNKALNAVVLESEYVLGKG----IVSKCQVNGNTYDICIGNEALILEDALK 731

  Fly   300 E--IILSLAD-----GLLEAGRHVRAFAYKELSDELEFRRFSQVNTGLEGGEYKYRDYLAVDTYS 357
            :  .|.|..|     ..:....||  |...|::||::...::.|       :|..|:
Yeast   732 KSGFINSNVDQGNTVSYVSVNGHV--FGLFEINDEVKHDSYATV-------QYLQRN-------- 779

  Fly   358 LRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQAVNLK 422
                                       |.:..::|......||.:|.:|||      :|:.|
Yeast   780 ---------------------------GYETYMITGDNNSAAKRVAREVGI------SFENV--- 808

  Fly   423 RMPPTAEVVDMSQYADEKPQHQRRHIEQLILNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGG 487
                         |:|..|..:.    .|:...||                  :.....|:|:|.
Yeast   809 -------------YSDVSPTGKC----DLVKKIQD------------------KEGNNKVAVVGD 838

  Fly   488 TLHDTPAMRSSHVGVA-KYGSAVMCEASADLILL------DTSFATLVSVVGDSRLLFENLKKAL 545
            .::|.||:..|.:|:| ..|:.:..|| ||:::|      ..|...|.:.:..|...|:.:|..|
Yeast   839 GINDAPALALSDLGIAISTGTEIAIEA-ADIVILCGNDLNTNSLRGLANAIDISLKTFKRIKLNL 902

  Fly   546 AYCLATNICNILVYLFFFLLGIPLYIHI---------MDELILAF-LVNLVPALTLI--YEPPE 597
            .:.|..||         |::.|.:.:.|         :..|.:|| .|::|.:..::  :.||:
Yeast   903 FWALCYNI---------FMIPIAMGVLIPWGITLPPMLAGLAMAFSSVSVVLSSLMLKKWTPPD 957

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	115/649 (18%)
CCC2	NP_010556.1	HMA	6..67	CDD:238219
		HMA	84..144	CDD:238219
		P-type_ATPase_Cu-like	259..938	CDD:319783	109/628 (17%)