Protein Alignment CG45062 and ENA2

DIOPT Version :9

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_010324.3
• Gene: ENA2 / 851609
• SGDID: S000002446
• Length: 1091
• Species: Saccharomyces cerevisiae
• Alignment Length: 856
• Identity: 178/856 - (20%)
• Similarity: 314/856 - (36%)
• Gaps: 263/856 - (30%)

  Fly    13 NMGLACTHAISGIGFAVALACGRNTEVGSM-------TDLCFKERSRSRSQK------------- 57
            |:..:.:..:.|....:.:....|:|:|.:       :.|..::.|:|..|.
Yeast   207 NLAFSSSAVVKGRAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFL 271

  Fly    58 --------HQK--QISYYMLLVAIVCFILLFLTTGFEHGHIVYEVNLSLLIGLTPVYLPFILYWG 112
                    |:|  :::..:..:|::..|::..:..|:....|....:.:.:.:.|..|..:|...
Yeast   272 GTNVGTPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLTIT 336

  Fly   113 LRRTRKEMGRKQCHVRNLRATCTLGLSTVIVSDLVGTMTKRRMRVSEIFVD-MGLLSVDNLD--- 173
            :......|..:...||.|.:...||....|.||..||:|:.:|...:|::. .|.:::.|.|
Yeast   337 MSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTITISNSDDPF 401

  Fly   174 ------VSAQSPRF---------------------------------IELIR-----------AS 188
                  ||. .|||                                 ::|.:           |:
Yeast   402 NPNEGNVSL-IPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDLFQKWLETATLANIAT 465

  Fly   189 VLCNDAVICPGNIGVPKMQKDMYGNILDIALLKFGL-MILPSIDLLRHDHEKVANKHYNSEDKVQ 252
            |..:||..|          ...:|:..:||:..|.. |.||...|   ..||..|:. |..|:..
Yeast   466 VFKDDATDC----------WKAHGDPTEIAIQVFATKMDLPHNAL---TGEKSTNQS-NENDQSS 516

  Fly   253 VTVHRTRDADGHLKLV-------------------------LLMKGHCEVVIRRCSTFAIRD--E 290
            ::.|..:......:.:                         :..||..|.:|..||::..:|  :
Yeast   517 LSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYGKGAFESIISCCSSWYGKDGVK 581

  Fly   291 ELPLDEQLQEIILSLADGLLEAGRHVRAFAYKELSDELEFRRFSQVNTGLEGGEYKYRDYL---- 351
            ..||.:...|.|......|...|..|..||.|..:.:       |||.          |.|
Yeast   582 ITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKD-------QVND----------DQLKNIT 629

  Fly   352 ---AVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPS 413
               |.....|.|||:|..|:|||:....||.:...|||.:.::|......|||:|.:|||||
Yeast   630 SNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKAIAQEVGILP--- 691

  Fly   414 DTFQAVNLKRMPPTAEVVDM-----SQY---ADEK---------------PQHQRRHIEQLILNQ 455
                 .||...  :.|:||.     ||:   ::|:               ||.:.|.||  .|::
Yeast   692 -----TNLYHY--SQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVRMIE--ALHR 747

  Fly   456 QDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGVAK--YGSAVMCEASADLI 518
            :...||.|                      |..::|:|:::.::||:|.  .||.|..||| |::
Yeast   748 RKKFCAMT----------------------GDGVNDSPSLKMANVGIAMGINGSDVSKEAS-DIV 789

  Fly   519 LLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICNILVYLFFFLL-----GIPLY-IHIMDEL 577
            |.|.:||::::.|.:.|.:.:|::|.:...||.|:...| ||...|:     |..:: :..::.|
Yeast   790 LSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQAL-YLIIGLVFRDENGKSVFPLSPVEVL 853

  Fly   578 ILAFLVNLVPALTLIYEPPEENLMLQMPKVYD--------DFLLNSRLFFVSHILVGTIEAAAVF 634
            .:..:.:..||:.|..|....:||.:.|  :|        :.::::  |....|:.|:..|:...
Yeast   854 WIIVVTSCFPAMGLGLEKAAPDLMDRPP--HDSEVGIFTWEVIIDT--FAYGIIMTGSCMASFTG 914

  Fly   635 MTYFVFMADKG---------------------FLPRTLVALNIAW------------HDDMLDDI 666
            ..|.:.....|                     |...|..||.:||            |.|....:
Yeast   915 SLYGINSGRLGHDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMHPDTDSPV 979

  Fly   667 TDSFGQEWSSE 677
            .:.|...|.::
Yeast   980 KEFFRSIWGNQ 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	E1-E2_ATPase	<13..132	CDD:278548	22/148 (15%)
		Cation_ATPase	190..284	CDD:289987	22/119 (18%)
		Cation_ATPase_C	582..777	CDD:295563	24/137 (18%)
ENA2	NP_010324.3	ATPase-IID_K-Na	11..1055	CDD:130586	178/856 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341387
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840