Protein Alignment CG45062 and ENA5

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_010323.3
• Gene: ENA5 / 851608
• SGDID: S000002445
• Length: 1091
• Species: Saccharomyces cerevisiae
• Alignment Length: 854
• Identity: 177/854 - (20%)
• Similarity: 313/854 - (36%)
• Gaps: 259/854 - (30%)

  Fly    13 NMGLACTHAISGIGFAVALACGRNTEVGSM-------TDLCFKERSRSRSQK------------- 57
            |:..:.:..:.|....:.:....|:|:|.:       :.|..::.|:|..|.
Yeast   207 NLAFSSSAVVKGRAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFL 271

  Fly    58 --------HQK--QISYYMLLVAIVCFILLFLTTGFEHGHIVYEVNLSLLIGLTPVYLPFILYWG 112
                    |:|  :::..:..:|::..|::..:..|:....|....:.:.:.:.|..|..:|...
Yeast   272 GTNVGTPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLTIT 336

  Fly   113 LRRTRKEMGRKQCHVRNLRATCTLGLSTVIVSDLVGTMTKRRMRVSEIFVD-MGLLSVDNLD--- 173
            :......|..:...||.|.:...||....|.||..||:|:.:|...:|::. .|.:::.|.|
Yeast   337 MSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTITISNSDDPF 401

  Fly   174 ------VSAQSPRF---------------------------------IELIR-----------AS 188
                  ||. .|||                                 ::|.:           |:
Yeast   402 NPNEGNVSL-IPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDLFQKWLETATLANIAT 465

  Fly   189 VLCNDAVICPGNIGVPKMQKDMYGNILDIALLKFGL-MILPSIDLLRHDHEKVANKHYNSEDKVQ 252
            |..:||..|          ...:|:..:||:..|.. |.||...|   ..||..|:. |..|:..
Yeast   466 VFKDDATDC----------WKAHGDPTEIAIQVFATKMDLPHNAL---TGEKSTNQS-NENDQSS 516

  Fly   253 VTVHRTRDADGHLKLV-------------------------LLMKGHCEVVIRRCSTFAIRD--E 290
            ::.|..:......:.:                         :..||..|.:|..||::..:|  :
Yeast   517 LSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYGKGAFESIISCCSSWYGKDGVK 581

  Fly   291 ELPLDEQLQEIILSLADGLLEAGRHVRAFAYKELSDELEFRRFSQVNTGLEGGEYKYRDYL---- 351
            ..||.:...|.|......|...|..|..||.|..:.:       |||.          |.|
Yeast   582 ITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKD-------QVND----------DQLKNIT 629

  Fly   352 ---AVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPS 413
               |.....|.|||:|..|:|||:....||.:...|||.:.::|......|||:|.:|||||
Yeast   630 SNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKAIAQEVGILP--- 691

  Fly   414 DTFQAVNLKRMPPTAEVVDM-----SQY---ADEK---------------PQHQRRHIEQLILNQ 455
                 .||...  :.|:||.     ||:   ::|:               ||.:.|.||  .|::
Yeast   692 -----TNLYHY--SQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVRMIE--ALHR 747

  Fly   456 QDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGVAK--YGSAVMCEASADLI 518
            :...||.|                      |..::|:|:::.::||:|.  .||.|..||| |::
Yeast   748 RKKFCAMT----------------------GDGVNDSPSLKMANVGIAMGINGSDVSKEAS-DIV 789

  Fly   519 LLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICNILVYLFFFLL-----GIPLY-IHIMDEL 577
            |.|.:||::::.|.:.|.:.:|::|.:...||.|:...| ||...|:     |..:: :..::.|
Yeast   790 LSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQAL-YLIIGLVFRDENGKSVFPLSPVEVL 853

  Fly   578 ILAFLVNLVPALTLIYEPPEENLMLQMPKVYD------DFLLNSRLFFVSHILVGTIEAAAVFMT 636
            .:..:.:..||:.|..|....:||.:.|...:      :.::::  |....|:.|:..|:.....
Yeast   854 WIIVVTSCFPAMGLGLEKAAPDLMDRPPNDSEVGIFTWEVIIDT--FAYGIIMTGSCMASFTGSL 916

  Fly   637 YFVFMADKG---------------------FLPRTLVALNIAW------------HDDMLDDITD 668
            |.:.....|                     |...|..||.:||            |.|....:.:
Yeast   917 YGINSGRLGHDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMHPDTDSPVKE 981

  Fly   669 SFGQEWSSE 677
            .|...|.::
Yeast   982 FFRSIWGNQ 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	177/854 (21%)
ENA5	NP_010323.3	ATPase-IID_K-Na	11..1055	CDD:130586	177/854 (21%)