Protein Alignment CG45062 and Atp13a2

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: XP_006539299.1
• Gene: Atp13a2 / 74772
• MGIID: 1922022
• Length: 1252
• Species: Mus musculus
• Alignment Length: 858
• Identity: 175/858 - (20%)
• Similarity: 294/858 - (34%)
• Gaps: 232/858 - (27%)

  Fly    31 LACG------------RNTEVGSMTDLCFKERSRSRSQKHQKQISYYMLLVAIVCFILLFLTTGF 83
            |.||            |...|.:.|..|..:.....|..|.:.||:..                :
Mouse   452 LFCGTLILQARAYVGPRVLAVVTRTGFCTAKGGLVSSILHPRPISFKF----------------Y 500

  Fly    84 EHGHIVYEVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRN--LRATCTLGLSTVIVSD- 145
            :|. :.:...||:|..|..||...|||           |.:..||.  :||   |.|.||:|..
Mouse   501 KHS-MKFVAALSVLALLGTVYSIIILY-----------RNRVPVREIVIRA---LDLVTVVVPPA 550

  Fly   146 LVGTMT------KRRMRVSEIFV------------------DMGLLSVDNLDVSAQSP------- 179
            |...||      :.|:|...||.                  ..|.|:.|.|||....|
Mouse   551 LPAAMTVCTLYAQSRLRTQGIFCIHPLRINLGGKLRLVCFDKTGTLTEDGLDVMGVVPLKGQVLL 615

  Fly   180 ---------RFIELIRASVLCNDAVICPGNIGVPKMQKDMYGNILDIALLKFGLMIL-------- 227
                     ....|:||...|:         .:.::.....|:.:|:.:::....:|
Mouse   616 PLVPEPCHLPLGPLLRALATCH---------ALSQLHDTPVGDPMDLKMVESTGWVLEEGPAAGS 671

  Fly   228 -PSIDLLRHDHEKVANKHYNSEDKVQVTV---------HRTRDA----DGHLKLVLLMKGHCEVV 278
             |...:|..............|..|.|:|         .:..|.    .|..:....:||..|:|
Mouse   672 APGSQVLVVMRPPPGGPRQQEEPPVPVSVLCRFPFSSALQRMDVVVTWPGATQPEAYVKGSPELV 736

  Fly   279 IRRCSTFAIRDEELPLDEQLQEIILSLADGLLEAGRHVRAFAYKELSDELEFRRFSQVNTGLEGG 343
            ...||     .|.:|.|  ..:::.|..    .||..|.|.|.|.|          .:...|...
Mouse   737 ASLCS-----PETVPSD--FSQVLQSYT----AAGYRVVALAGKPL----------PIAPSLAAA 780

  Fly   344 EYKYRDYLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGI 408
            :...||.:..:   |..||::...|..:......:...|..||:.::||....:.|..:|...|:
Mouse   781 QQLTRDTVERE---LSLLGLLVMRNLLKPQTAPVIQTLRKTGIRTVMVTGDNLQTAVTVARACGM 842

  Fly   409 LPAPS----------DTFQAVNLKRMPPTAEVVDMSQYAD-----EKPQH------------QRR 446
            :.|..          :..|...|:.:|..:..|.....|.     .:||.            .|:
Mouse   843 VGAQEHLAVIHATHPEQGQPAALEFLPTESSAVMNGAKATGYPTVPEPQSCHLALSGSTFAVLRK 907

  Fly   447 HIEQLI--LNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGVAKYGSAV 509
            |..:|:  :..|..|.|..:.:|...:....:||...|.:.|...:|..|::::.||::
Mouse   908 HFPKLLPKVLVQATVFARMAPEQKTELVCELQRLQYCVGMCGDGANDCGALKAADVGIS------ 966

  Fly   510 MCEASADLILLDTSFATLV----SVVGDSR----LLFENLKKALAYCLATNICNILVYLFFFLLG 566
            :.:|.|.::...||....:    :|:.:.|    ..|...|....|.|...|..:::|.....||
Mouse   967 LSQAEASVVSPFTSSMASIECVPTVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLG 1031

  Fly   567 IPLYIHIMDELILAFLVNLV-----PALTLI-YEPPEENLMLQMPKVYDDFLLNSRLFFVSHILV 625
            ...::.|  :|::...|.::     |||||: ..||  ..:|.:|      :|.|.|..|:  ||
Mouse  1032 DLQFLAI--DLVITTTVAVLMSRTGPALTLVRARPP--GALLSVP------VLGSLLLQVA--LV 1084

  Fly   626 GTIEAAAVFMTYFVFMADKGFLP--RTL------------VALNIAWHDDMLDDITDSFGQEWSS 676
            ..|:...    ||:.:|...|:|  ||:            |..:::....::.....|.|..:
Mouse  1085 AGIQLGG----YFLVIAQPWFVPLNRTVPAPDNLPNYENTVVFSLSGFQYLILAAAVSKGAPF-- 1143

  Fly   677 EARRQLECQVSSLCLMSLAVMQCTNLVLT------KTGRANLLAHGFRNWLLSLAVLLLICLCVQ 735
              |:.|...|..|..::|.......|:|.      ..|..|::...|:..||.|.....:...:.
Mouse  1144 --RQPLYTNVPFLVALALLGSVLVGLILVPGLLQGPLGLRNIVDSSFKLLLLGLVAFNFVGAFML 1206

  Fly   736 LCIMDSTV--CLR 746
            ..::|..:  |||
Mouse  1207 ESVLDQCLPACLR 1219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	175/858 (20%)
Atp13a2	XP_006539299.1	P-ATPase-V	35..1195	CDD:273738	170/832 (20%)