Protein Alignment CG45062 and atp13al

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: XP_004914468.2
• Gene: atp13al / 733496
• XenbaseID: XB-GENE-5883964
• Length: 1245
• Species: Xenopus tropicalis
• Alignment Length: 839
• Identity: 151/839 - (17%)
• Similarity: 261/839 - (31%)
• Gaps: 292/839 - (34%)

  Fly    24 GIGFAVALACGRNTEVGSMTDLCFKERSRSRSQKHQKQISYYML-----LVAIVCFILLFLTTGF 83
            |:..||.|..|.||..|.:.          ||..:.|.|.:.:.     ::|.:..:.:|
 Frog   359 GLVKAVVLHTGFNTTKGDLV----------RSILYPKPIKFKLYKDVFWVIAALSVVSVF----- 408

  Fly    84 EHGHIVYEVNLSLLIGLTP---VYLPFILYWGLRRTRKEMGRKQCHVRNLRATCTLGLSTVIVSD 145
               .::|.|.:..|.|..|   |.:.||:                      .||.:.:|......
 Frog   409 ---GLIYSVVVGALQGAEPKDLVLMGFIM----------------------LTCAVPVSLPPALA 448

  Fly   146 LVGTMTKRRMRVSEIFV------------------DMGLLSVDNLD----VSAQSPRFIE----- 183
            :....::.|::...||.                  ..|.|:.:.||    |.::...|.|
 Frog   449 VCVLYSQNRLKKHGIFCISPDRISLCGQLNLICFDKTGTLTEEGLDLWGIVPSRENCFQEAHHFT 513

  Fly   184 ---------LIRASVLCNDAVICPGNIGVPKMQKDMYGNILDIALLK-FGLMILPSIDLLRHDHE 238
                     |:.|...|:..::..|.|         :|:.||..:.: .|..|..|......|.:
 Frog   514 SGSTLPWGPLLGAVASCHSLIVLDGAI---------HGDPLDFKMFEGSGWNIDESQATCTVDGK 569

  Fly   239 --KVANKHYNSEDKVQV-------------TVHR---TRDADGHLKLVLLMKGHCEVVIRRCSTF 285
              ........|..||.|             .:.|   .....|..:|.|.:||..|:|:|.|
 Frog   570 CCSCVTVKPGSGSKVPVDGINILLQFPFSSALQRMSVVAQVIGEQRLTLFLKGAPEMVVRFC--- 631

  Fly   286 AIRDEELPLDEQLQEIILSLADGLLEAGRHVRAFAYK--ELSDELEFRRFSQVNTGLEGGEYKYR 348
              :.|.:|      ....:..|...|.|..|.:.|||  ||.:.:......             |
 Frog   632 --KQETVP------SSFKNTLDYYTEQGFRVISLAYKYFELEENISLPNLK-------------R 675

  Fly   349 DYLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILP--- 410
            :.:..|   |.|||.:...|..:......:....:|.::.:::|....|.|..:.:..|::|
 Frog   676 EEVESD---LIFLGFLIMENQLKPETKPVLQELVSANLRTVMLTGDNLKTACTVGMGSGMVPSTD 737

  Fly   411 ----------------------------------------------------------APSDTFQ 417
                                                                      |.|.|:.
 Frog   738 NVFLLEATEYEEGTQPFINWQILKRNKDNDTKLNETTVNILCTDNAIKCNTIQNKLDYATSGTYY 802

  Fly   418 AVNLKRMP------------------PTAEVVDMSQYAD----EKP------QHQ---------- 444
            :.:.:.:|                  |:...|..|:..:    |.|      ||:
 Frog   803 STDKQNLPELMMPNVCLLPSVFADVAPSVAAVAFSKTGENIQSESPSSHYIKQHKYHYAMTGNSY 867

  Fly   445 ---RRHIEQL----ILNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGV 502
               ::|...|    :||  ..:.|..:..|...:.:..:.:...|.:.|...:|..|::.:|.|:
 Frog   868 QTIKQHFPDLMPDILLN--GTIFARMTPKQKSTMIEDLQNIDYYVGMCGDGANDCGALKMAHAGI 930

  Fly   503 AKYGSAVMCEASADLILLDTSFATLVS----VVGDSRLLFEN----LKKALAYCLATNICNILVY 559
            :      :.|..|.:....||..|.::    ::.:.|.:|..    .|..:.|.....||..|::
 Frog   931 S------LSELEASVASPFTSKITNITCMPILLKEGRNVFVTYISLFKYMVMYAFIGLICMFLMF 989

  Fly   560 LFFFLLGIPLY----IHIMDELILAFLVNLVPALTLIYEPPEENLMLQMPKVYDDFLLNSRLFFV 620
            ....:||...|    |.|...|:|...:| .||..|....|...|:|..       ||.|.:..:
 Frog   990 WEQTILGSNQYLMQDIAITIPLMLTLSLN-GPAPKLAPYRPAGRLLLPP-------LLLSIILHL 1046

  Fly   621 SHILVGTIEAAAVFMTYFVFMADKGF---------LPRTLVALNIAWHDDMLDDITDSF 670
            |..|  |::..|    |||......|         :|:.:...|..  ..|..||:.:|
 Frog  1047 SFTL--TVQMCA----YFVLQQQPWFSRTDVFYACIPQNMSFANQT--SPMEYDISQNF 1097

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	151/839 (18%)
atp13al	XP_004914468.2	P5-ATPase	18..138	CDD:463565
		Haloacid Dehalogenase-like Hydrolases	170..1066	CDD:473868	144/804 (18%)