Protein Alignment CG45062 and Atp2b1

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_001346435.1
• Gene: Atp2b1 / 67972
• MGIID: 104653
• Length: 1249
• Species: Mus musculus
• Alignment Length: 746
• Identity: 158/746 - (21%)
• Similarity: 298/746 - (39%)
• Gaps: 183/746 - (24%)

  Fly    16 LACTHAISGIGFAVALACGRNTEVG-------------------------SMTDLCFKERSRSRS 55
            |:.||.:.|.|..|..|.|.|::.|                         ...|...:.|:::::
Mouse   261 LSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQDGAIENRNKAKA 325

  Fly    56 Q-----------------------------KHQKQI---------------SYYMLLVAIVCFIL 76
            |                             |.:|.:               ...|..:.::..:|
Mouse   326 QDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVL 390

  Fly    77 LFLTTGF----------------EHGHIVYEVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQC 125
            .|:...|                ::....:.:.:::|:...|..||..:...|..:.|:|.:...
Mouse   391 YFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNN 455

  Fly   126 HVRNLRATCTLGLSTVIVSDLVGTMTKRRMRVSEIFV-DMGLLSVDNLDVSAQSPRFIELIRASV 189
            .||:|.|..|:|.:|.|.||..||:|..||.|.:.:: :.....|.  :..|..|..:..:...:
Mouse   456 LVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVP--EPEAIPPNILSYLVTGI 518

  Fly   190 LCNDA----VICPGNI-GVPKMQKDMYGNILDIALLKFGLMILPSIDLLRHDHEKVANK------ 243
            ..|.|    ::.|... |:|:    ..||..:.|||.|      .:||.| |::.|.|:
Mouse   519 SVNCAYTSKILPPEKEGGLPR----HVGNKTECALLGF------LLDLKR-DYQDVRNEIPEEAL 572

  Fly   244 ----HYNSEDKVQVTVHRTRDADGHLKLVLLMKGHCEVVIRRC----------STFAIRDEELPL 294
                .:||..|...||  .:::||..:  :..||..|:::::|          ..|..||.:
Mouse   573 YKVYTFNSVRKSMSTV--LKNSDGSFR--IFSKGASEIILKKCFKILSANGEAKVFRPRDRD--- 630

  Fly   295 DEQLQEIILSLADGLLEAGRHVRAFAYKEL---SDELEFRRFSQVNTGLEGGEYKYRDYLAVDTY 356
                 :|:.::.:.:...|......|:::.   ..|.|:...:.|.||
Mouse   631 -----DIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDVVTG----------------- 673

  Fly   357 SLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQAVNL 421
             |..:.::...:|.|..:|:|:.:|:.|||.:.:||......|:|:|...||| .|.:.|..:..
Mouse   674 -LTCIAVVGIEDPVRPEVPEAIKKCQRAGITVRMVTGDNINTARAIATKCGIL-HPGEDFLCLEG 736

  Fly   422 KRMPPTAEVVDMS-QYADEKPQHQRRHIEQLILNQQDLVCAATSTDQ---LHWIADA-CRRLGAV 481
            |         |.: :..:||.:.::..|:: |..:..::..::.||:   :..|.|: ......|
Mouse   737 K---------DFNRRIRNEKGEIEQERIDK-IWPKLRVLARSSPTDKHTLVKGIIDSTVSEQRQV 791

  Fly   482 VSVIGGTLHDTPAMRSSHVGVAK--YGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLKKA 544
            |:|.|...:|.||::.:.||.|.  .|:.|..||| |:||.|.:|.::|..|...|.:::::.|.
Mouse   792 VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEAS-DIILTDDNFTSIVKAVMWGRNVYDSISKF 855

  Fly   545 LAYCLATNICNILVYLFFFLLGIPLYIHIMDELILAFLVNLVPALTLIYEPPEENLMLQMPKVYD 609
            |.:.|..|:..::|......:.....:..:..|.:..:::.:.:|.|..|||.|:|:|:.|
Mouse   856 LQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKP---- 916

  Fly   610 DFLLNSRLFFVSHILVGTIEAAAVFMTYFVF 640
             :..|..|  :|..::..|...|.:....||
Mouse   917 -YGRNKPL--ISRTMMKNILGHAFYQLVVVF 944

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	158/746 (21%)
Atp2b1	NP_001346435.1	ATPase-IIB_Ca	15..1064	CDD:273668	158/746 (21%)
		ATP_Ca_trans_C	1103..1178	CDD:463575