Protein Alignment CG45062 and atp1a3a

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_571759.2
• Gene: atp1a3a / 64610
• ZFINID: ZDB-GENE-001212-7
• Length: 1023
• Species: Danio rerio
• Alignment Length: 838
• Identity: 248/838 - (29%)
• Similarity: 424/838 - (50%)
• Gaps: 111/838 - (13%)

  Fly    13 NMGLACTHAISGIGFAVALACGRNTEVGSMTDLCF-KERSRSRSQKHQKQISYYMLLVAI---VC 73
            |:....|:.:.|....:.:..|..|.:|.:..|.. .|..::...|..:...:.:..||:   |.
Zfish   241 NIAFFSTNCVEGTARGIVVCTGDRTVMGRIATLTSGLETGKTPIAKEIEHFIHIITGVAVFLGVT 305

  Fly    74 FILLFLTTGFEH--------GHIVYEVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRNL 130
            |.:|.:..|:..        |.||..|...||..:|..         |..|.|.|.||.|.|:||
Zfish   306 FFILSIILGYSWLEAVIFLIGIIVANVPEGLLATVTVC---------LTLTAKRMARKNCLVKNL 361

  Fly   131 RATCTLGLSTVIVSDLVGTMTKRRMRVSEIFVDMGLLSVDNLD------VSAQSPRFIELIRASV 189
            .|..|||.::.|.||..||:|:.||.|:.::.|..:...|..:      ....|..::.|.|.:.
Zfish   362 EAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGASFDKSSGTWLALARVAA 426

  Fly   190 LCNDAVICPGNIGVPKMQKDMYGNILDIALLKFGLMILPSIDLLRHDHEKVANKHYNSEDKVQVT 254
            |||.||...|...:|.:::|:.|:..:.||||...:...|:..:|..::|||...:||.:|.|::
Zfish   427 LCNRAVFKAGQESLPILKRDVAGDASESALLKCIELSCGSVKAMRDKNKKVAEIPFNSTNKYQLS 491

  Fly   255 VHRTRDADGHLKLVLLMKGHCEVVIRRCSTFAIRDEELPLDEQLQEI--------------ILSL 305
            ||...:::.: ..:|:|||..|.::.||||...:.:|.|:||:|:|.              :|..
Zfish   492 VHELDESEEN-HYLLVMKGAPERILDRCSTILQQGKEQPMDEELKEAFQNAYLELGGLGERVLGF 555

  Fly   306 ADGLLEAGRHVRAFAYKELSDELEFRRFSQVNTGLEGGEYKYRDYLAVDTYSLRFLGMIATYNPP 370
            ...::...::.:.||:.  :|::.|:                       |.:|.|:|:::..:||
Zfish   556 CHLVMPGDKYPKGFAFD--TDDINFQ-----------------------TDNLCFVGLMSMIDPP 595

  Fly   371 RSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQAVNLKRMPPTAEV----- 430
            |:.:|.||.:||:||||:|:||...|..|||:|..|||:...::|.:.:..:...|.::|
Zfish   596 RAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDA 660

  Fly   431 -------VDMSQYADEKPQHQRRHIEQLILNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGT 488
                   .|:...:.::       :::::.|..::|.|.||..|...|.:.|:|.||:|:|.|..
Zfish   661 KACVIHGTDLKDLSQDQ-------MDEVLKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDG 718

  Fly   489 LHDTPAMRSSHVGVAK--YGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLKKALAYCLAT 551
            ::|:||::.:.:|||.  .||.|..:| ||:||||.:||::|:.|.:.||:|:||||::||.|.:
Zfish   719 VNDSPALKKADIGVAMGISGSDVSKQA-ADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTS 782

  Fly   552 NICNILVYLFFFLLGIPLYIHIMDELILAFLVNLVPALTLIYEPPEENLMLQMPK-VYDDFLLNS 615
            ||..|..:|||.|:.|||.:..:..|.:....::|||::|.||..|.::|.:.|: ...|.|:|.
Zfish   783 NIPEITPFLFFILVNIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPLRDKLVNE 847

  Fly   616 RLFFVSHILVGTIEAAAVFMTYFVFMADKGFLPRTLVALNIAWHDDMLDDITDSFGQEWSSEARR 680
            ||..:::..:|.|:|...|.:|||.:|:.||||..||.:.:.|.|...:|:.||:||:|:.|.|:
Zfish   848 RLISIAYGQIGMIQALGGFFSYFVILAENGFLPSVLVGIRLNWDDRSNNDLEDSYGQQWTYEQRK 912

  Fly   681 QLECQVSSLCLMSLAVMQCTNLVLTKTGRANLLAHGFRNWLL--------SLAVLLLICLCVQLC 737
            .:|....:...:|:.|:|..::::.||.|.::...|.:|.:|        :||..|..|..
Zfish   913 IVEFTCHTAFFVSIVVVQWADVIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPG---- 973

  Fly   738 IMDSTVCLRLEGTN-ELHFGHFLLTNCPFMILLVFIETTRRYFIRLFPDSWLELATMY 794
             ||  |.||:.... ...|..|     |:..|:...:..|:..:|..|..|:|..|.|
Zfish   974 -MD--VALRMYPLKPSWWFCAF-----PYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1023

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	247/836 (30%)
atp1a3a	NP_571759.2	ATPase-IIC_X-K	30..1023	CDD:273445	247/836 (30%)