Protein Alignment CG45062 and atp1a2a

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_571758.1
• Gene: atp1a2a / 64609
• ZFINID: ZDB-GENE-001212-6
• Length: 1017
• Species: Danio rerio
• Alignment Length: 831
• Identity: 259/831 - (31%)
• Similarity: 420/831 - (50%)
• Gaps: 98/831 - (11%)

  Fly    13 NMGLACTHAISGIGFAVALACGRNTEVGSMTDLCFKERSRSRSQKHQ----KQISYYMLLVAIVC 73
            |:....|:.:.|....:.:|.|.:|.:|.:..|.      |..:..|    .:|.:::.::..|.
Zfish   236 NISFFSTNCVEGTAHGIVIATGDHTVMGRIATLA------SGLEVGQTPINMEIEHFIHIITGVA 294

  Fly    74 ------FILLFLTTG--------FEHGHIVYEVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQ 124
                  |.:|.:..|        |..|.||..|...||..:|..         |..|.|.|.||.
Zfish   295 IFLGMSFFILSIILGYTWLEAVIFLIGIIVANVPEGLLATVTVC---------LTLTAKRMARKN 350

  Fly   125 CHVRNLRATCTLGLSTVIVSDLVGTMTKRRMRVSEIFVDMGLLSVD------NLDVSAQSPRFIE 183
            |.|:||.|..|||.::.|.||..||:|:.||.|:.::.|..:...|      ..|....||.:..
Zfish   351 CLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGCDFDKSSPTWFS 415

  Fly   184 LIRASVLCNDAVICPGNIGVPKMQKDMYGNILDIALLKFGLMILPSIDLLRHDHEKVANKHYNSE 248
            |.|...|||.||...|...:|...:|..|:..:.||||...::..:::.||.::.|||...:||.
Zfish   416 LSRVGGLCNRAVFKAGQEEIPIRTRDTAGDASESALLKCVEILSGNVETLRGNNRKVAEIPFNST 480

  Fly   249 DKVQVTVHRTRDA-DGHLKLVLLMKGHCEVVIRRCSTFAIRDEELPLDEQLQEIILSLADGLLEA 312
            :|.|:::|...|: .|||   |:|||..|.::.||||..|...|.|:|:...:........|...
Zfish   481 NKYQLSIHELEDSPTGHL---LVMKGAPERILDRCSTIMINGVEFPIDDDWMDAFQGAYMELGGL 542

  Fly   313 GRHVRAFAYKELSDELEFRRFSQVNTGLEGGEYKYRDYLAVDTYSLRFLGMIATYNPPRSTIPKA 377
            |..|..|.:..||.. :|.|         |.|:...| :......|.|||:|:..:|||:.:|.|
Zfish   543 GERVLGFCHLFLSPS-QFPR---------GFEFDCDD-VNFPVNQLCFLGLISMVDPPRAAVPDA 596

  Fly   378 VDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQAVNLKRMPPTAEV------------ 430
            |.:||:||||:|:||...|..|||:|..|||:...::|.:.:..:...|.::|
Zfish   597 VGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAERLNIPLSQVNPREAKACVVHG 661

  Fly   431 VDMSQYADEKPQHQRRHIEQLILNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAM 495
            .|:...:.|       :::.::.|..::|.|.||..|...|.:.|:|.||:|:|.|..::|:||:
Zfish   662 SDLKDMSSE-------YLDDILRNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPAL 719

  Fly   496 RSSHVGVAK--YGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICNILV 558
            :.:.:|||.  .||.|..:| ||:||||.:||::|:.|.:.||:|:||||::||.|.:||..|..
Zfish   720 KKADIGVAMGITGSDVSKQA-ADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITP 783

  Fly   559 YLFFFLLGIPLYIHIMDELILAFLVNLVPALTLIYEPPEENLMLQMPK-VYDDFLLNSRLFFVSH 622
            :|.|.:..:||.:..:..|.:....::|||::|.||..|.::|.:.|: ...|.|:|.||..:::
Zfish   784 FLLFIIASVPLPLGTVTILCIDLGTDMVPAISLAYESAESDIMKRQPRNPKTDKLVNERLISMAY 848

  Fly   623 ILVGTIEAAAVFMTYFVFMADKGFLPRTLVALNIAWHDDMLDDITDSFGQEWSSEARRQLECQVS 687
            ..:|.|:|...|.||||.||:.||||:||:.:.:.|.|..::|:.|.:||:|:.|.|:.:|....
Zfish   849 GQIGMIQALGGFFTYFVIMAENGFLPQTLLGIRLDWDDRTVNDLEDGYGQQWTYEQRKIIEFTCH 913

  Fly   688 SLCLMSLAVMQCTNLVLTKTGRANLLAHGFRNWLL--------SLAVLLLICLCVQLCIMDSTVC 744
            :...:|:.|:|..:|::.||.|.::...|.:|.:|        :||..|..|..     ||  |.
Zfish   914 TSFFVSIVVVQWADLIICKTRRNSVFQQGMKNRILIFGLFAETALAAFLSYCPG-----MD--VA 971

  Fly   745 LRLEGTNEL-HFGHFLLTNCPFMILLVFIETTRRYFIRLFPDSWLELATMY 794
            ||:.....: .|..|     |:.:|:...:..|::.:|..|..|:|:.|.|
Zfish   972 LRMYPLKIMWWFCAF-----PYSLLIFVYDEIRKFILRRNPGGWVEIETYY 1017

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	258/829 (31%)
atp1a2a	NP_571758.1	ATPase-IIC_X-K	34..1017	CDD:273445	258/829 (31%)