Protein Alignment CG45062 and atp2a1

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: XP_012810385.1
• Gene: atp2a1 / 613090
• XenbaseID: XB-GENE-975115
• Length: 996
• Species: Xenopus tropicalis
• Alignment Length: 855
• Identity: 188/855 - (21%)
• Similarity: 352/855 - (41%)
• Gaps: 182/855 - (21%)

  Fly    13 NMGLACTHAISGIGFAVALACGRNTEVGSMTD-LCFKERSRSRSQKHQKQISYYM-LLVAIVCFI 75
            ||..:.|:..:|....|.:|.|.|||:|.:.| :...|:.::..|:...:....: .:::::|..
 Frog   206 NMLFSGTNVGAGKAIGVVIATGPNTEIGKIRDEMAATEQEKTPLQQKLDEFGEQLSKVISLICVA 270

  Fly    76 LLFLTTG----------FEHGHIVY-EVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRN 129
            :..:..|          :..|.|.| ::.::|.:...|..||.::...|....:.|.:|...||:
 Frog   271 VWLINIGHFNDPIHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRS 335

  Fly   130 LRATCTLGLSTVIVSDLVGTMTKRRMRVSEIF----VDMGLLSVDNLDV--SAQSPR-------- 180
            |.:..|||.::||.||..||:|..:|.|..:|    ||..:.|::...:  |..:|.
 Frog   336 LPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVLDKVDGDICSLNEFSITGSTYAPEGEVLKNDK 400

  Fly   181 ---------FIELIRASVLCNDAVICPGNIGVPKMQKDMYGNILDIALL----KFGLMILPSIDL 232
                     .:||.....||||:.:   :....|...:..|...:.||.    |..:.......|
 Frog   401 SVKAGQYDGLVELATICALCNDSSL---DYNESKGVFEKVGEATETALTTLVEKMNVFNTEVRSL 462

  Fly   233 LRHDHEKVAN--------KHYN---SEDKVQVTVHRT-----RDADGHLKLVLLMKGHCEVVIRR 281
            .:.:.....|        |.:.   |.|:..::|:.|     |.|.|:   .:.:||..|.||.|
 Frog   463 SKVERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPAKASRAAVGN---KMFVKGAPEGVIDR 524

  Fly   282 CSTFAIRDEELPLDEQLQEIILSLADGLLEAGR-----HVRAFAYKELSDELEFRRFSQVNTGLE 341
            |:...:....:||...:::.||::   :.|.|.     ...|.|.::...:.|........
 Frog   525 CNYVRVGTTRVPLTPAIKDKILTV---IKEWGTGRDTLRCLALATRDTPPKREEMVLDDAT---- 582

  Fly   342 GGEYKYRDYLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDV 406
                |:.||   :| .|.|:|.:...:|||..:..::..||.|||::|::|......|.|:...:
 Frog   583 ----KFVDY---ET-DLTFVGCVGMLDPPRKEVMGSIKLCREAGIRVIMITGDNKGTAIAICRRI 639

  Fly   407 GILPAPSD----TFQAVNLKRMPPTAE---VVDMSQYADEKPQHQRRHIEQLILNQQDLVCAATS 464
            ||.....|    .|.......:|||.:   ....|.:|..:|.|:.:.:|.|           .|
 Frog   640 GIFGEDDDVSRCAFTGREFDDLPPTEQREACKRASCFARVEPTHKSKIVEFL-----------QS 693

  Fly   465 TDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGVAKYGSAVMCEASADLILLDTSFATLVS 529
            .|:             :.::.|..::|.||::.:.:|:|......:.:.:::::|.|.:|:|:|:
 Frog   694 FDE-------------ITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVA 745

  Fly   530 VVGDSRLLFENLKKALAYCLATNICNILVYLFFFLLGIPLYIHIMDELILAFL--VNLV----PA 588
            .|.:.|.::.|:|:.:.|.:::|:..::.......||:|      :.||...|  ||||    ||
 Frog   746 AVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLP------EALIPVQLLWVNLVTDGLPA 804

  Fly   589 LTLIYEPPEENLMLQMPKVYDDFLLNSRLFFVSHILVGTIEAAAVFMTYFVFM-ADKGFLPRTLV 652
            ..|.:.||:.::|.:.|:...:.|::..|||....:.|.:.||.|....:.|| ||.|  |. :.
 Frog   805 TALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYLAIGGYVGAATVGAAAWWFMYADDG--PE-VT 866

  Fly   653 ALNIAWHDDMLDDITDSFGQEWSSEARRQLECQV------SSLCLMSLAVMQCTNLVLTKTGRAN 711
            ...::......::..|..|          |||::      .::.|..|..::..|.:.:.:...:
 Frog   867 FYQLSHFMQCTEENADFEG----------LECEIFESPVPMTMALSVLVTIEMCNALNSLSENQS 921

  Fly   712 L--LAHGFRNWLLSLAVLLLICLCVQLCIMDSTVCLRLEGTNELHFGHFLLTNCPFMILLVFIET 774
            |  :......|||                  .::||.:    .|||            |::::|.
 Frog   922 LVRMPPWVNIWLL------------------GSICLSM----SLHF------------LILYVEP 952

  Fly   775 TRRYFIRLFP 784
            ....| :|.|
 Frog   953 LPMIF-KLTP 961

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	188/855 (22%)
atp2a1	XP_012810385.1	P-type_ATPase_SERCA	5..989	CDD:319778	188/855 (22%)