Protein Alignment CG45062 and atp7a

DIOPT Version :9

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: NP_001036185.1
• Gene: atp7a / 564924
• ZFINID: ZDB-GENE-060825-45
• Length: 1482
• Species: Danio rerio
• Alignment Length: 587
• Identity: 119/587 - (20%)
• Similarity: 214/587 - (36%)
• Gaps: 175/587 - (29%)

  Fly    37 TEVGSMTDL-----CFKERSRSRS--QKHQKQISYY---MLLVAIVCFILLFLTTGFEHGHIVYE 91
            |.||:.|.|     ..:|...|::  |:...:||.|   .::|..|..:|.::..||
Zfish   890 THVGTDTTLSQIVKLVEEAQTSKAPIQQFADKISSYFVPFIVVISVLTLLAWIIIGF-------- 946

  Fly    92 VNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVR----------NLRATCTLGLSTVIVSDL 146
            ||.||:....|.|            .|.:...:..:|          .:...|:|||:|. .:.:
Zfish   947 VNFSLVQTYFPGY------------DKSISEAEAVIRFAFQASITVLCIACPCSLGLATP-TAVM 998

  Fly   147 VGTMTKRRMRVSEIFVDMGLLSVDNLDVSAQSPRFIEL---IRASVLCNDAVICPGNIGVPKMQK 208
            |||               |:.:.:.:.:....|  :|:   |::.|......|   ..|.||
Zfish   999 VGT---------------GVGAQNGILIKGGEP--LEMAHKIQSVVFDKTGTI---TYGAPK--- 1040

  Fly   209 DMYGNILDIALLKFGLMILPSIDLLRHDHEKVANKHYNSEDKVQVTVHRTRDADGHLKLVLLMKG 273
                 ::.:.:|..|.. ||...||    ..|.....:||..:...:  |:.....|....|  |
Zfish  1041 -----VVQVKMLAEGNR-LPRSKLL----AIVGTAENSSEHPLGAAI--TKYCKQELGTESL--G 1091

  Fly   274 HC-----------EVVIRRCSTFAIRDEELPLDEQLQEIILSLADGLLEAGRH-----------V 316
            .|           ..::........|::....:.|...:::.::|....:..|           |
Zfish  1092 TCTDFQAVPGCGIRCLVSNTENLLKREDSDSEENQHNAVLIQISDARAHSTEHPLIMDPQPLTVV 1156

  Fly   317 RAFAYKELSDELEFRRFS--QVNTGLEGG--EYKYRD----YLAVDTYSLRFLGMIATYNPPRST 373
            :..:|..|....|:.|.:  ||...::..  |::.|.    .:|||.   ....|:|..:..:..
Zfish  1157 QTASYTVLIGNREWMRRNALQVRADVDEAMTEHERRGCTAVLVAVDN---ELCAMVAIADTVKPE 1218

  Fly   374 IPKAVDRCRAAGIKLIVVTQRKPKMAKALAVDVGILPAPSDTFQAVNLKRMPPTAEVVDMSQYAD 438
            ...||....|.|::::::|....|.|:|:|..|||                        ...:|:
Zfish  1219 AELAVHVLSAMGLEVVLMTGDNSKTARAIAAQVGI------------------------RKVFAE 1259

  Fly   439 EKPQHQRRHIEQLILNQQDLVCAATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGVA 503
            ..|.|:...:|||                        ::.|..|:::|..::|:||:..:.||:|
Zfish  1260 VLPSHKVAKVEQL------------------------QQAGKRVAMVGDGVNDSPALAMADVGIA 1300

  Fly   504 -KYGSAVMCEASADLILLDTSFATLVSVVGDSRLLFENLKKALAYCLATNICNILVYLFFFLLGI 567
             ..|:.|..|| ||::|:...   |:.|||...|..:.:|:..        .|.:..|.:.|:||
Zfish  1301 IGTGTDVAIEA-ADVVLIRND---LLDVVGSIDLSKKTVKRIR--------INFVFALMYNLVGI 1353

  Fly   568 PL 569
            |:
Zfish  1354 PI 1355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	E1-E2_ATPase	<13..132	CDD:278548	24/114 (21%)
		Cation_ATPase	190..284	CDD:289987	18/104 (17%)
		Cation_ATPase_C	582..777	CDD:295563
atp7a	NP_001036185.1	HMA	11..74	CDD:238219
		HMA	174..237	CDD:238219
		HMA	279..336	CDD:238219
		HMA	362..424	CDD:238219
		HMA	477..539	CDD:238219
		ZntA	550..1377	CDD:225127	119/587 (20%)
		HMA	552..615	CDD:238219
		E1-E2_ATPase	771..1018	CDD:278548	34/165 (21%)
		HAD_like	1171..1324	CDD:304363	45/207 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573944
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930