Protein Alignment CG45062 and atp2a1l

DIOPT Version :10

• Sequence 1: NP_001286726.1
• Gene: CG45062 / 19835139
• FlyBaseID: FBgn0266432
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: XP_005156129.1
• Gene: atp2a1l / 494489
• ZFINID: ZDB-GENE-041229-2
• Length: 993
• Species: Danio rerio
• Alignment Length: 864
• Identity: 197/864 - (22%)
• Similarity: 374/864 - (43%)
• Gaps: 168/864 - (19%)

  Fly    13 NMGLACTHAISGIGFAVALACGRNTEVGSMTD-LCFKERSRSRSQKHQKQISYYM-LLVAIVCFI 75
            ||..:.|:..:|....||:|.|..||:|.:.| :...|:.::..|:...:....: .:::::|..
Zfish   206 NMLFSGTNIAAGKAVGVAVATGVATEIGKIRDQMAATEQEKTPLQQKLDEFGEQLSKVISLICVA 270

  Fly    76 LLFLTTG----------FEHGHIVY-EVNLSLLIGLTPVYLPFILYWGLRRTRKEMGRKQCHVRN 129
            :..:..|          :..|.:.| ::.::|.:...|..||.::...|....:.|.:|...||:
Zfish   271 VWMINIGHFNDPVHGGSWIRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRS 335

  Fly   130 LRATCTLGLSTVIVSDLVGTMTKRRMRVSEIFV----DMGLLSVDNLDVS--------------- 175
            |.:..|||.::||.||..||:|..:|.|:::||    |...:.:|:.|:|
Zfish   336 LPSVETLGCTSVICSDKTGTLTTNQMCVTKMFVIDRIDGDHVELDSFDISGSKYTPEGEVTKLGA 400

  Fly   176 ----AQSPRFIELIRASVLCND---------------------AVICPGNIGVPKMQ--KDMYGN 213
                :|....:||.....||||                     |:.|.    |.||.  |...||
Zfish   401 KVDCSQYDGLVELATICALCNDSSLDYNETKKIYEKVGEATETALCCL----VEKMNVFKSNVGN 461

  Fly   214 ILDIALLKFGLMILPSIDLLRHDHEKVANKHYN---SEDKVQVTVHRTRDADGHLKLVLLMKGHC 275
            :..:........::          :::..|::.   |.|:..::|:.| ...|.....:.:||..
Zfish   462 LSKVERANACCSVV----------KQLMKKNFTLEFSRDRKSMSVYCT-PVKGDAGSKMFVKGAP 515

  Fly   276 EVVIRRCSTFAIRDEELPLDEQLQEIILSLADGLLE--AGRH-VRAFAYKELSDELEFRRFSQVN 337
            |.||.||:...:....:||...:::.|:::   :.|  .||. :|..|.......|:....:
Zfish   516 EGVIDRCTYVRVGSTRVPLTGAVKDKIMNV---IKEWGTGRDTLRCLALATRDSPLKVEEMN--- 574

  Fly   338 TGLEGGEYKYRDYLAVDTYSLRFLGMIATYNPPRSTIPKAVDRCRAAGIKLIVVTQRKPKMAKAL 402
              ||... |:.||   :| .|.|:|.:...:|||..:..:::.||||||::|::|......|.|:
Zfish   575 --LEDST-KFADY---ET-DLTFVGCVGMLDPPRKEVTGSIELCRAAGIRVIMITGDNKGTAVAI 632

  Fly   403 AVDVGILPAPSD-TFQAVNLKRMP--PTAEVVDMSQ----YADEKPQHQRRHIEQLILNQQDLVC 460
            ...:||.....| |.:|...:...  |.:|..:..:    :|..:|.|:.:.:|  .|...|.:.
Zfish   633 CRRIGIFSEDEDVTGKAYTGREFDDLPHSEQSEAVRRACCFARVEPSHKSKIVE--FLQGYDEIT 695

  Fly   461 AATSTDQLHWIADACRRLGAVVSVIGGTLHDTPAMRSSHVGVAKYGSAVMCEASADLILLDTSFA 525
            |.|                      |..::|.||::.:.:|:|......:.:::::::|.|.:|:
Zfish   696 AMT----------------------GDGVNDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFS 738

  Fly   526 TLVSVVGDSRLLFENLKKALAYCLATNICNILVYLFFFLLGIPLYIHIMDELILAFL--VNLV-- 586
            ::|:.|.:.|.::.|:|:.:.|.:::||..::.......||:|      :.||...|  ||||
Zfish   739 SIVAAVEEGRAIYNNMKQFIRYLISSNIGEVVCIFLTAALGLP------EALIPVQLLWVNLVTD 797

  Fly   587 --PALTLIYEPPEENLMLQMPKVYDDFLLNSRLFFVSHILVGT-IEAAAVFMTYFVFMADKGFLP 648
              ||..|.:.||:..:|.:.|:...:.|::..||| .::.||. :.||.|....:.|:.|:....
Zfish   798 GLPATALGFNPPDLEIMGKPPRSPKEPLISGWLFF-RYMTVGAYVGAATVAAAAYWFIYDEEGPQ 861

  Fly   649 RTLVALN--IAWHDDMLDDITDSFGQEWSSEARRQLECQVSSLC---LMSLAVM----QCTNLVL 704
            .|...|:  :..|::. :|.|.             :||:|...|   .|:|:|:    .|..|..
Zfish   862 VTYYQLSHFMQCHEEN-EDFTG-------------IECEVFEACPPMTMALSVLVTIEMCNALNS 912

  Fly   705 TKTGRANLLAHGFRN-WLLSLAVLLLICLCVQLCIMD-STVCLRLEGTNELHFGHFLLTNCPFMI 767
            ....::.:....:.| |||| |:.|.:.|...:..:| ..:..||...|...:  |::....|.:
Zfish   913 LSENQSLVRMPPWSNGWLLS-AMTLSMSLHFMIIYVDPMPMIFRLTHLNTEQW--FVVLKLSFPV 974

  Fly   768 LLVFIETTRRYFIRLFPDS 786
            :|  |:...::..|.:.|:
Zfish   975 IL--IDEMLKFLARNYVDA 991

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45062	NP_001286726.1	ATPase-IIC_X-K	<13..794	CDD:273445	197/864 (23%)
atp2a1l	XP_005156129.1	P-type_ATPase_SERCA	5..986	CDD:319778	195/857 (23%)